Indications

Ulipristal Acetate is indicated for emergency contraception within 120 hours (5 days) of unprotected sexual intercourse or contraceptive failure.

Pharmacology

Ulipristal Acetate is an orally active synthetic SPRM that works by binding to the human progesterone receptor with high affinity. The principal mechanism of action is ovulation inhibition or delay. Ulipristal Acetate has been shown to delay follicular rupture in some women even when administered right before ovulation.

Dosage & Administration

One 30 mg tablet must be taken as soon as possible but no later than 120 hours of unprotected intercourse or contraceptive failure, with or without food. If vomiting occurs within 3 hours of intake, then another tablet needed to be taken. Ulipristal Acetate can be taken at any time of the menstrual cycle.

Interaction

Barbiturates, Carbamazepine, Phenobarbital, Rifampicin, Itraconazole, Ketoconazole, and other medications interact with Ulipristal Acetate.

Contraindications

Ulipristal Acetate should not be used if you have a hypersensitivity to active ingredients or if you are pregnant.

Side Effects

The most common side-effects are headache, nausea, abdominal pain, dysmenorrhea, fatigue, dizziness, breast tenderness, etc.

Pregnancy & Lactation

It’s not a good idea to take it if you’re pregnant or think you’re pregnant. Breast milk excretes ulipristal acetate. As a result, breastfeeding should be avoided for the first week following consumption. There is very little information on the health of a pregnancy or newborn exposed to Ulipristal acetate.

Precautions & Warnings

Existing Pregnancy: Ulipristal Acetic acid derivation isn’t shown for the end of an existing pregnancy. Ectopic Pregnancy: A history of ectopic pregnancy isn’t a contraindication to the utilization of this crisis prophylactic method. Repeated Utilize: Ulipristal Acetic acid derivation is for incidental utilize as a crisis prophylactic. It ought to not supplant a customary strategy of contraception. Rehashed utilization of Ulipristal Acetate within the same menstrual cycle isn’t suggested, as the security and viability of rehash utilization inside the same cycle have not been evaluated. Fertility Taking after Utilize: A fast return of ripeness is likely taken after treatment with Ulipristal Acetic acid derivation for crisis contraception. So, to anticipate pregnancy on an afterward scene of sexual intercut one ought to utilize the boundary strategy (ex. Condom).

Therapeutic Class

Drugs that affect the uterus, such as the emergency contraceptive pill

Storage Conditions

Store in a cool, dry location away from direct sunlight. Do not allow yourself to become frozen. Keep out of children’s reach.

Generic

Ulipristal Acetate [For emergency contraception]

Pharmaceutical Name

Ziska Pharmaceuticals Ltd.