Ursodil 150 MG


Ursodil 150 MG


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Ursodeoxycholic Acid



Ursodeoxycholic Acid is indicated for the treatment of

  • Cholestasis (Jaundice)
  • Viral Hepatitis
  • Alcoholic Fatty Liver
  • Primary Billiary Cirrhosis (PBC)
  • Primary Sclerosing Cholangitis (PSC)
  • Dissolution of Gallstones and Non-Alcoholic Steato Hepatitis (NASH).



Ursodeoxycholic Corrosive may be a normally happening bile corrosive utilized to treat distinctive hepatobilliary disarranges. The action of Ursodeoxycholic Corrosive is accomplished through a diminish in emission of cholesterol in bile. Ursodeoxycholic Corrosive accomplishes this through a couple of components: it diminishes cholesterol retention, smothers liver cholesterol amalgamation and it does not hinder bile corrosive synthesis. Therefore, changes bile composition from supersaturated to unsaturated. Ursodeoxycholic Corrosive moreover advances the arrangement of fluid cholesterol precious stone complexes which upgrade expulsion of the cholesterol from the gallbladder into the digestive system to be removed. Ursodeoxycholic Corrosive makes strides cholestatic liver infections by- Protecting cholangiocytes against cytotoxicity of hydrophobic bile acids Stimulating hepatobilliary secretion Protecting hepatocytes against bile acid-induced apoptosis Ursodeoxycholic Corrosive is totally retained within the upper digestive tract. Time to top serum concentration changes from 30 to 15.


Administration & Dosage

Dissolution of Gall stones: 8-12 mg/kg/day either as single night time dose or in divided doses.

Primary Billiary Cirrhosis: 10-15 mg/kg/day in 2-4 divided doses.

Acute Viral Hepatitis: 600 mg/day.

Alcoholic Fatty Liver: 300 mg/day.

Primary Sclerosing Cholangitis: 25-30 mg/kg/day.

Dissolution of Gallstones and Non-Alcoholic Steato Hepatitis: 13-15 mg/kg/day.



Ursodeoxycholic Acid should not be used with drugs, such as oestrogenic hormones, that increase bile cholesterol. Concomitant administration with bile-acid binding drugs including antacids, charcoal and cholestyramine should be avoided, since this may reduce the effectiveness of therapy with Ursodeoxycholic acid.



Non-functioning gall-bladder calcified and pigmented gallstones, inflammatory bowel disease.


Side Effects

Commonly reported side effects are nausea, vomiting, diarrhoea, gallstone opacilication, pruritus.


Pregnancy & Lactation

Pregnancy category B. No evidence of harm has been reported in pregnancy. It has been effectively used for the treatment of cholestasis of pregnancy during the last trimester without any side effects. Problems have not been documented in humans regarding breast feeding.


Precautions & Warnings

It should be used cautiously in those with liver disease.


Therapeutic Class

Anti-gallstones drugs: Bile Acids


Storage Conditions

Protect from light and moisture by storing below 30°C. Keep the medicine out of children’s reach.


Pharmaceutical Name

General Pharmaceuticals Ltd.