Tycil 500MG


Tycil 500MG


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Indications of Tycil 500mg Capsule

Tycil 500mg Capsule is used to treat infections caused by bacteria that are sensitive to the ß-lactamase enzyme. These infections include the following:

  • Infections of the ears, nose, and throat (i.e. otitis media, sinusitis, tonsillitis, pharyngitis, laryngitis)
  • Infections of the lower respiratory tract (i.e. pneumonia, acute and chronic bronchitis lung abscess, empyema, bronchiectasis)
  • Infections affecting the skin and soft tissues (i.e. cellulitis, carbuncles, furunculosis, infected wounds, abscess)
  • Infections of the genito-urinary tract (i.e. pyelonephritis, cystitis and urethritis)
  • Venereal illness is a kind of venereal infection (i.e. acute uncomplicated gonorrhoea)
  • It is used as a short-term treatment for tooth abscesses.
  • It’s also used in conjunction with Clarithromycin and Lansoprazole (called triple therapy) to treat H. pylori infection and duodenal ulcer illness, as well as to minimize the chance of recurrence of the ulcer.


Pharmacology of Tycil 500mg Capsule

Tycil 500mg Capsule is penicillin with a broad spectrum of activity. It works against a variety of Gram-positive and Gram-negative bacteria. It works by preventing the production of cell walls. In the presence of stomach acid, amoxicillin is stable and is readily absorbed after oral administration. Amoxicillin reaches its maximal plasma concentration approximately 1 to 2 hours after oral dosage. Amoxicillin is extensively disseminated in bodily tissues and fluids at different concentrations.


Tycil 500mg Capsule Dosage

Adult: 250 mg three times daily, increasing up to 500 mg three times daily for severe infections.

Children (up to 10 years of age): 125 mg three times daily, increasing up to 250 mg three times daily for severe infections.

  • Severe or recurrent purulent respiratory infection: 3 gm every 12 hours.
  • Otitis media: The recommended dose is 1 g three times daily for adults and 40 mg/kg body weight daily in 3 divided doses for children (max. 3 g daily).
  • Pneumonia: The recommended dose is 500-1000 mg three times daily.
  • Dental abscess: The recommended dose is 3 gm, repeated after 10-12 hours.
  • Urinary tract infections: The recommended dose is 3 gm, repeated after 10-12 hours.
  • Gonorrhea: Single dose of 2-3 gm with Probenecid 1 gm is recommended (Probenecid is contraindicated in children under 2 years).
  • In renal impairment: it may be necessary to reduce the total daily dosage.



Reconstituted suspension can be administered by adding the required amount of suspension to milk, fruit juice, water. These preparations should then be taken immediately.


Interaction of Tycil 500mg Capsule

When you take Amoxicillin and Probenecid together, your blood levels of Amoxicillin may rise and stay high for a long time. Amoxicillin may alter gut flora, resulting in decreased estrogen reabsorption and decreased effectiveness of combination estrogen/progesterone contraceptives.


Contraindications of Tycil 500mg Capsule

Tycil 500mg Capsule is not recommended for people who are allergic to penicillin.


Tycil 500mg Capsule Side Effects

The side effects are minor and only last a short time. Diarrhea, indigestion, and rash are all possible symptoms. Only a few cases of pseudo-membranous colitis have been recorded.


Pregnancy & Lactation

Amoxicillin is classified as a pregnancy category B by the US Food and Drug Administration. However, no appropriate and well-controlled trials in pregnant women have been conducted. Because animal reproduction studies do not always anticipate human response, this medication should only be taken during pregnancy if absolutely necessary. Human milk has been found to contain amoxicillin. When administering Amoxicillin to a breastfeeding mother, care should be used.


Precautions & Warnings

During treatment, keep in mind the risk of superinfection with mycotic or bacterial diseases. If superinfections develop, Amoxicillin should be stopped and proper treatment started.


Therapeutic Class

Broad spectrum penicillins


Storage Conditions

Keep away from light and heat in a dry area. Keep out of children’s reach.


Pharmaceutical Name of Tycil 500mg Capsule

Beximco Pharmaceuticals Ltd.



Amoxicillin Trihydrate