Trilock 10 MG

102510014201403

Trilock 10 MG

16.00৳ 

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In Stock

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Description

Generic

Montelukast Sodium

 

Indications

Trilock 10 mg is prescribed for the prevention and treatment of asthma. Exercise-Induced Bronchoconstriction: Acute Prevention (EIB). Allergic Rhinitis (AR) Symptom Relief: Seasonal & Perennial Allergic Rhinitis

 

Pharmacology

Trilock 10 mg inhibits the cysteinyl leukotriene receptor and is a selective and orally active leukotriene receptor antagonist (CysLT1). Arachidonic acid metabolism produces cysteinyl leukotrienes (LTC4, LTD4, LTE4), which are secreted by a variety of cells, including mast cells and eosinophils. The pathophysiology of asthma and allergic rhinitis, including airway edema, smooth muscle contraction, and altered cellular activity associated with the inflammatory process, have been linked to cysteinyl leukotrienes and leukotriene receptor occupation, all of which contribute to the signs and symptoms of asthma.

 

Dosage and Administration

Adults & adolescents (15 years & older)-

  • Asthma & Allergic Rhinitis: 10 mg/day
  • Exercise-Induced Bronchoconstriction: 10 mg/day

Pediatric patients (6 to 14 years)-

  • Asthma & Allergic Rhinitis: 5 mg/day
  • Exercise-Induced Bronchoconstriction: 5 mg/day

Pediatric patients (6 months to 5 years)-

  • Asthma & Allergic Rhinitis: 4 mg/day
  • Exercise-Induced Bronchoconstriction: Not recommended

Patients with both asthma and allergic rhinitis should take only one dose daily in the evening. For prevention of Acute prevention of Exercise-Induced Bronchoconstriction, a single dose should be taken at least 2 hours before exercise.

 

Interaction

When Trilock 10 mg is combined with theophylline, prednisone, prednisolone, terfenadine, digoxin, warfarin, gemfibrozil, itraconazole, thyroid hormones, sedative-hypnotics, non-steroidal anti-inflammatory agents, benzodiazepines, decongestants, oral contraceptives, and CYP enzyme inducers, no dose adjustment is required.

With regard to food and others: With food and other conditions, bioavailability and other variables were not significantly noticed.

 

Contraindications

Trilock 10 mg is contraindicated in patients who are hypersensitive to any component of this product.

 

Side Effects

Diarrhea, fever, gastrointestinal distress, headache, nausea, vomiting, skin responses, and upper respiratory tract infection are all common symptoms.

Akathisia, anxiety, arthralgia, asthenia, aberrant behavior, depression, dizziness, drowsiness, dry mouth, hemorrhage, irritability, malaise, muscle complaints, edema, seizure, anomalous feeling, sleep disturbances are all uncommon symptoms.

Angioedema, disorientation, eosinophilic granulomatosis with polyangiitis, erythema nodosum, hallucination, hepatic problems, memory loss, palpitations, pulmonary eosinophilia, suicidal tendencies, tremors are all uncommon symptoms.

 

Pregnancy & Lactation

In pregnant women, there are no sufficient and well-controlled trials. Trilock 10 mg should only be used during pregnancy if it is absolutely necessary. Montelukast is a medication that is secreted in breast milk. When Trilock 10 mg is given to a nursing woman, vigilance should be observed.

 

Precautions & Warnings

Trilock 10 mg is not recommended for bronchospasm reversal in acute asthma attacks, including status asthmatic. Agitation, anger, anxiety, depression, disorientation, attention disturbances, dream abnormalities, hallucinations, insomnia, irritability, memory impairment, restlessness, somnambulism, suicidal thinking and behavior (including suicide), and tremors are all neuropsychiatric occurrences.

 

Therapeutic Class

Leukotriene receptor antagonists

 

Storage Conditions

Store in a cool & dry place below 30°C, and protect from light & moisture. Keep out of reach of children.

 

Pharmaceutical Name

Opsonin Pharma Limited