Generic

Vitamin B1, B6 & B12

Indications

Vitamins B1, B6 and B12 are suitable for the treatment of vitamin B1, B6 and B12 deficiencies. It is also suitable for the supportive treatment of neuritis and inflammatory diseases of neurons, such as

• Diabetic neuropathy
• Peripheral neuralgin
• Lumbago
• Myalgia
• Optic neuritis
• Sciatica
• Facial neuralgia
• Intercostal neuralgia
• Spinal pain.

Pharmacology

Vitamin B1 converts carbohydrates, fatty acids and amino acids into energy, promotes nerve health, improves mood and strengthens the heart. Vitamin B6 forms erythrocytes and cells help produce protein, and produce, for example, neurotransmitters. Cellotonin and stored form Energy release can help prevent CVS disease and stroke, and reduce depression and insomnia. Vitamin B 12 is essential for cell replication and red blood cell production. It can prevent anemia and help prevent depression and help reduce neuralgia, growth and dangers of heart disease.

Vitamins are well absorbed orally. It is widely distributed in most tissues and is present in breast milk. In the cell, thiamine mainly exists in the form of diphosphate. Thiamine is not stored in the body at any significant level, and the amount that exceeds the body’s needs will be excreted in the urine in the form of thiamine or unchanged metabolites. After oral administration, pyridoxine, pyridoxal and pyridoxamine are easily absorbed from the gastrointestinal tract and converted into the active forms of pyridoxal phosphate and pyridoxamine phosphate. They are stored primarily in the liver, where they are oxidized to pyridoxine and other inactive metabolites, which are then excreted in the urine. As the dose increases, the amount of urine excreted in its original form increases proportionally.

Dosage & Administration

Tablet: 1-3 Tablets per day or as advised by the physician.

Injection:

• In severe (acute) cases: 1 injection daily until the acute symptoms subside or taken as advised by the physician.
• In mild cases: 1 injection 2-3 times per week. Ampoules are preferably injected intramuscularly.

Use in children: There is no information on the use of this drug in children.

Contraindications

Vitamin B1, vitamin B6 and vitamin B12 are contraindicated in patients receiving treatment with levodopa and in patients allergic to any ingredient in the preparation.

Side Effects

It is generally well tolerated, but in some cases allergic reactions can be seen.

Pregnancy

The oral tablet form is recommended, but due to the presence of benzyl alcohol, injection is not recommended during pregnancy and while breastfeeding.

Precautions

Patients with subacute spinal cord degeneration should not use cyanocobalamin. Cyanocobalamin is not a suitable form of vitamin B12 and is used to treat optic neuropathy associated with elevated plasma levels of cyanocobalamin.

Therapeutic Class

Specific combined vitamin preparations

Storage Conditions

Pharmaceutical Name

ACME Laboratories Ltd.