Teviral 0.5 MG


Teviral 0.5 MG


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Indications of Teviral 0.5 Tablet

Entecavir is indicated for the treatment of chronic hepatitis B virus infection in adults with compensated liver disease, evidence of viral replication and histologically documented active liver inflammation or fibrosis. It is also effective in decompensated cirrhosis.


Pharmacology of Teviral 0.5 Tablet

Entecavir is a guanosine nucleoside analogue with potent and selective activity against HBV polymerase. For pharmacological action it is phosphorylated to the active triphosphate (TP) form. Entecavir triphosphate functionally inhibits all 3 activities of the viral polymerase-

  • Priming of the HBV polymerase,
  • Reverse transcription of the negative strand from the pregenomic messenger RNA
  • Synthesis of the positive strand HBV DNA.


Dosage & Administration of Teviral 0.5 Tablet

Administration of Entecavir with food decreases absorption and so it should be taken in an empty stomach (at least 2 hours before or 2 hours after meal).


Interaction of Teviral 0.5 Tablet

Coadministration with medications that decrease renal function or compete for active tubular secretion may increase serum concentrations of either drug because Entecavir is primarily removed by the kidney.



Patients who have previously shown hypersensitivity to Entecavir or any component of the medicine should not use it.


Side Effects of Teviral 0.5 Tablet

The most common side effects are headache, fatigue, dizziness and nausea.


Pregnancy & Lactation

Use in pregnancy: There are no adequate and well-controlled studies in pregnant women. Entecavir should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.


Precautions & Warnings

Every 3 months, check liver function tests, and every 3-6 months, check viral and serological markers for hepatitis B. If you notice a change in your liver function, hepatic steatosis, progressive hepatomegaly, or unexplained lactic acidosis, stop taking it. Discontinuation may result in recurrent hepatitis.


Therapeutic Class

Hepatic viral infections (Hepatitis B)


Storage Conditions

Keep the temperature below 30°C and away from light and moisture. Keep out of children’s reach.


Pharmaceutical Name of Teviral 0.5 Tablet

ACI Limited


Generic of Teviral 0.5 Tablet