Tenoloc 50 MG


Tenoloc 50 MG


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Indications of Tenoloc 50

Tenoloc 50 is demonstrated-

Within the administration of hemodynamically steady patients with definite or suspected intense myocardial dead tissue to diminish cardiovascular mortality.

For the long-term administration of patients with angina pectoris. Within the administration of hypertension. It may be utilized alone or concomitantly with other antihypertensive operators, especially with a thiazide-type diuretic.


Pharmacology of Tenoloc 50

The amalgamation of atenolol brought about from endeavors to create a β-adrenoceptor enemy that would competitively square β1 (cardiac) receptors but have no impact on β2-receptors. It is classified as a β1 specific (cardioselective) β-adrenergic receptor enemy with no membrane stability action and no fractional agonist action. It is extraordinarily the foremost hydrophilic of the as of now accessible β- blockers and in this way enters the lipid of cell films ineffectively


Dosage and Administration

Hypertension: The introductory measurement of Atenolol is 50 mg given as one tablet a day either alone or included in diuretic treatment. The complete impact of this dosage will as a rule be seen inside one to two weeks. On the off chance that an ideal reaction isn’t accomplished, the measurement ought to be expanded to Atenolol 100 mg given as one tablet a day. Expanding the dose past 100 mg a day is impossible to deliver any assist benefit.

Angina Pectoris: The starting measurements of Atenolol is 50 mg given as one tablet a day. In the occasion that an ideal reaction isn’t accomplished within one week, the dose ought to be expanded to Atenolol 100 mg given as one tablet a day. A few patients may require a dose of 200 mg once a day for ideal impact. Twenty-four-hour control with once day-by-day dosing is accomplished by giving measurements larger than fundamental to attain a prompt greatest impact. The most extreme early impact on workout resistance happens with dosages of 50 to 100 mg, but at these measurements, the impact at 24 hours is weakened, averaging around 50% to 75% of that watched with once-a-day verbal dosages of 200 mg.

Intense Myocardial Localized corruption: In patients with positive or suspected intense myocardial dead tissue, treatment with Atenolol I.V. Infusion ought to be started as before long as conceivable after the patient’s entry within the clinic and after qualification is set up. Treatment ought to start with the intravenous organization of 5 mg Atenolol over 5 minutes taken after by another 5 mg intravenous infusion 10 minutes afterward. In patients who endure the total intravenous measurements (10 mg), Atenolol Tablets 50 mg ought to be started 10 minutes after the final intravenous measurements are taken by another 50 mg verbal dosage 12 hours afterward. From there on, Atenolol can be given orally either 100 mg once every day or 50 mg twice a day for an assist 6-9 days or until release from the clinic. In the occasion that bradycardia or hypotension requiring treatment or any other untoward impacts happen, Atenolol ought to be ceased.

Interaction of Tenoloc 50

Catecholamine-depleting drugs (eg, reserpine) may have an added substance impact when given with beta-blocking specialists. Patients treated with Atenolol additionally a catecholamine depletion ought to in this manner be closely watched for prove of hypotension and/or stamped bradycardia which may create vertigo, syncope, or postural hypotension.

Calcium channel blockers may too have an added substance impact when given with Atenolol.

Disopyramide may be a Sort I antiarrhythmic medicate with strong negative inotropic and chronotropic impacts. Disopyramide has been related to serious bradycardia, asystole, and heart disappointment when managed with beta-blockers.

Amiodarone is an antiarrhythmic specialist with negative chronotropic properties which will be added substance to those seen with beta-blockers.

Beta-blockers may compound bounce-back hypertension which can take after the withdrawal of clonidine. On the off chance that the two drugs are coadministered, the beta-blocker ought to be pulled back a few days sometime recently the continuous withdrawal of clonidine. In the occasion that supplanting clonidine by beta-blocker treatment, the presentation of beta-blockers ought to be postponed for a few days after clonidine organization has halted.

Concomitant utilize of prostaglandin synthase repressing drugs, eg, indomethacin, may diminish the hypotensive impacts of beta-blockers.

While taking beta-blockers, patients with a history of anaphylactic response to an assortment of allergens may have a more extreme response on the rehashed challenge, either inadvertent, symptomatic, or helpful. Such patients may be inert to the regular measurements of epinephrine utilized to treat the unfavorably susceptible reaction.

Both digitalis glycosides and beta-blockers moderate atrioventricular conduction and diminish heart rate. Concomitant utilize can increment the chance of bradycardia.


Tenoloc 50 is contraindicated in sinus bradycardia, heart square more noteworthy than to start with a degree, cardiogenic stun, and unmistakable cardiac disappointment. Those patients with a history of extreme touchiness to the atenolol or any of the medicate product’s components.

Side Effects of Tenoloc 50

In an arrangement of examinations within the treatment of intense myocardial dead tissue, bradycardia and hypotension happened more commonly, as anticipated for any beta-blocker. In expansion, an assortment of antagonistic effects has been detailed with other beta-adrenergic blocking specialists and may be considered potential antagonistic effects of Atenolol.

Hematologic: Agranulocytosis.

Allergic: Fever, combined with hurting and sore throat, laryngospasm, and respiratory distress.

Central Anxious Framework: Reversible mental discouragement advancing to catatonia; an intense reversible disorder characterized by confusion of time and put; brief term memory misfortune; passionate lability with marginally clouded sensorium; and, diminished execution on neuropsychometrics.

Gastrointestinal: Mesenteric blood vessel thrombosis, ischemic colitis.

Miscellaneous: There have been reports of skin rashes and/or dry eyes related to the utilize of beta-adrenergic blocking drugs. Discontinuance of the medicate ought to be considered on the off chance that any such response isn’t something else logical. Patients ought to be closely observed taking after cessation of therapy.

Other: Erythematous hasty


Pregnancy & Lactation

Pregnancy Category D. Caution ought to be worked out when Atenolol is managed by a nursing lady. Clinically critical bradycardia has been detailed in breastfed newborn children. Untimely newborn children, or newborn children with impeded renal work, may be more likely to create unfavorable impacts.


Precautions & Warnings

Common: Patients as of now on a beta-blocker must be assessed carefully sometime recently Atenolol is managed. Beginning and ensuing Atenolol measurements can be balanced descending depending on clinical perceptions counting beat and blood weight.

Atenolol may disturb fringe blood vessel circulatory disorders.  Impaired Renal Work: The sedate ought to be utilized with caution in patients with disabled renal work.

Geriatric Use:

Hypertension and Angina Pectoris: Due to Coronary Atherosclerosis: Measurements choice for an elderly quiet ought to be cautious, more regularly than not beginning at the moo conclusion of the dosing extend, reflecting the more prominent recurrence of diminished hepatic, renal, or cardiac work, and of concomitant illness or other sedate treatment. Intense Myocardial Dead tissue: Dosage choice for an elderly understanding ought to be cautious, ordinarily beginning at the moo conclusion of the dosing extend, reflecting more prominent recurrence of diminished hepatic, renal, or cardiac work, and of concomitant illness or other sedate treatment. Assessment of patients with hypertension or myocardial dead tissue ought to continuously incorporate evaluation of renal work.


Therapeutic Class

Beta-adrenoceptor blocking drugs, Beta-blockers


Storage Conditions

Don’t utilize afterward than the date of expiry. Keep all medications out of the reach of children. To be apportioned as it were on the medicine of an enrolled doctor.


Pharmaceutical Name of Tenoloc 50

Acme Laboratories Ltd


Generic of Tenoloc 50