Indications of Tabis 5 Tablet

Bisoprolol is indicatedin-

• Hypertension
• Angina
• Moderate to severe heart failure

Pharmacology of Tabis 5 Tablet

The most selective ß1 blocker is Bisoprolol Hemifumarate. It has the highest affinity for the ß1 receptor of any beta-blocker currently on the market. Blocks the ß1 adrenergic receptor in the heart and vascular smooth muscle, lowering heart rate and cardiac output and lowering arterial blood pressure. In patients with non-ß1 selective ß1-blockers, ß-blockers can impact lipid metabolism, however Bisoprolol does not produce any changes in the cholesterol fraction, including the cardioprotective HDL-cholesterol, over long-term medication.

Dosage & Administration of Tabis 5 Tablet

Hypertension: The dose of Bisoprolol must be individualized to the needs of the patient. The usual starting dose is 5 mg once daily. In some patients, 2.5 mg may be an appropriate starting dose. If the antihypertensive effect of 5 mg is inadequate, the dose may be increased to 10 mg and then, if necessary, to 20 mg once daily.

Angina: Usually 10 mg once daily (5 mg may be adequate in some patients) max 20 mg daily.

Heart Failure: Initially 1.25 mg once daily (in the morning) for 1 week then, if well tolerated, increased to 2.5 mg once daily for 1 week, then 3.75 mg once daily for 1 week, then 5 mg once daily for 4 weeks, then- 7.5 mg once daily for 4 weeks, then 10 mg once daily maximum 10 mg daily.

Interaction of Tabis 5 Tablet

Bisoprolol should not be combined with other ß-blocking agents.

Contraindications

In patients with cardiogenic shock, overt heart failure, second or third degree A-V block, right ventricular failure secondary to pulmonary hypertension and sinus bradycardia.

Side Effects of Tabis 5 Tablet

It is possible to experience gastrointestinal disorders, bradycardia, hypotension, headache, fatigue, sleep disturbances, dizziness, vertigo, thrombocytopenia, vision disturbances, and alopecia.

Pregnancy & Lactation

The safety of bisoprolol during pregnancy has not been established. No data is available for lactation.

Precautions & Warnings

Monitoring of renal, hepatic and hematopoietic function should be performed at regular intervals during long-term treatment with bisoprolol.

Therapeutic Class

Anti adrenergic agent (Beta blockers), Beta-adrenoceptor blocking drugs, Beta-blockers

Storage Conditions

Keep in a dry place away from light and heat. Keep out of the reach of children.

Pharmaceutical Name of Tabis 5 Tablet

Navana Pharmaceuticals Ltd

Generic of Tabis 5 Tablet

Bisoprolol Fumarate