Description
Indications of T-Mycin Plus 5 ml
This sterile Eye Suspension is used to treat steroid-responsive inflammatory ocular diseases in which a corticosteroid is prescribed yet there is a risk of bacterial eye infection.
Pharmaceutical Name of T-Mycin Plus 5 ml
Aristopharma Ltd.
Pharmacology
Tobramycin’s bactericidal activity is achieved, like that of other amino-glycosides, by inhibiting normal protein synthesis in susceptible bacteria, but nothing is understood about how this action works at the moment. Protein synthesis suppression is hypothesized to be caused by a ribosome activity that causes bacterial messenger RNA misreading. Dexamethasone works by inhibiting phospholipase A2, which is the first step in prostaglandin formation. Dexamethasone also prevents neutrophils from chemo-tactically infiltrating the inflammatory site.As a result, it has a 25-fold higher anti-inflammatory activity and an 8-10-fold higher overall therapeutic effectiveness than hydrocortisone.
Dosage & Administration
Interaction of T-Mycin Plus 5 ml
This combination eye drop has not been subjected to any particular interaction studies. In the case of simultaneous therapy with other topical ophthalmic drugs, a 10-minute delay between applications should be given.
Contrainidications
Side Effects of T-Mycin Plus 5 ml
Localized ocular toxicity and hypersensitivity, including lid irritation and swelling, as well as conjuntival erythema, are the most common side effects of topical ocular Tobramycin. The steroid component causes an increase in intraocular pressure (IOP), which can lead to glaucoma and infrequent optic nerve injury, as well as the production of posterior subcapsule cataracts.
Pregnancy & Lactation
It has not been determined whether or not it is safe to use during pregnancy and lactation in humans.
Precautions & Warnings
Before using, give the bottle a good shake. To avoid contamination, avoid touching the bottle’s tip to the affected eye, eyelid, or any other surface of the affected eye. After each usage, carefully shut the bottle.
Therapeutic Class
Combinations of ophthalmic steroid and antibiotic formulations
Storage Conditions
Allow to cool to room temperature before using. After each usage, immediately close the bottle. After opening the bottle, do not use it for more than one month.
Generic of T-Mycin Plus 5 ml
Dexamethasone + Tobramycin
