Description
Indications of T-Cef 400
- Uncomplicated urinary tract contaminations caused by Escherichia coli and Proteus mirabilis.
- Otitis Media caused by Haemophilus influenzae, Moraxella catarrhalis and Streptococcus pyogenes.
- Pharyngitis and tonsillitis caused by Streptococcus pyogenes.
- Acute bronchitis and intense exacerbations of unremitting bronchitis caused by Streptococcus pneumoniae and Haemophilus influenzae.
- Uncomplicated gonorrhea (cervical/urethral) caused by Neisseria gonorrhoeae.
Pharmaceutical Name of T-Cef 400
Drug International Ltd.
Pharmacology
Cefixime may be a third era semisynthetic cephalosporin anti-microbial for verbal organization. It is bactericidal against a wide range of gram positive and gram negative microbes at effortlessly achievable plasma concentrations. It murders microscopic organisms by interferometer within the union of bacterial cell divider. It is profoundly steady within the nearness of Beta-lactamase protein. As a result, numerous living beings safe to penicillins and a few cephalsporins due to the nearness of beta-lactamases, may be vulnerable to Cefixime. Assimilation of it is almost 40% to 50% whether managed with or without nourishment.
Dosage & Administration of T-Cef 400
- ½-1 year: 75 mg daily.
- 1-4 a long time: 100 mg daily.
- 5-10 a long time: 200 mg daily.
- 11-12 a long time: 300 mg daily
Interaction of T-Cef 400
Carbamazepine: Concomitant utilize raises the carbamazepine level. Warfarin and other anticoagulants: Concomitant utilize increments prothrombin time.
Contraindications
It is contraindicated in touchiness to Cefixime or other cephalosporins.
Side Effects of T-Cef 400
The medicate is by and large well endured. The foremost visit side impacts are loose bowels and stool changes; that have been more commonly related with higher measurements. Other side impacts are sickness, stomach torment, dyspepsia, spewing, tooting, headache and tipsiness. Hypersensitivities within the frame of hasty, pruritus, urticaria, medicate fever and arthralgia have been detailed. These responses more often than not died down upon dicontinuation of treatment.
Pregnancy & Lactation
There are, be that as it may, no satisfactory and well-controlled considers in pregnant ladies. Since creature propagation thinks about are not continuously prescient of human reaction, this medicate ought to be utilized amid pregnancy as it were on the off chance that clearly required. It isn’t known that Cefixime is excreted in human drain. So, caution ought to be worked out when Cefixime is managed to a nursing lady.
Precautions & Warnings
Therapeutic Class
Third generation Cephalosporins
Storage Conditions
Keep underneath 30ºC temperature, ensured from light & dampness. Keep out of the reach of children.
Generic Nmae of T-Cef 400
Cefixime Trihydrate
