Suma Nasal Spray 60 METERED


Suma Nasal Spray 60 METERED


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  • In adults, sumatriptan is used to treat acute migraines with or without aura.
  • Limitations of Use: Only use if you have a firm diagnosis of migraine headache.
  • The preventative treatment of migraine attacks is not recommended.
  • Cluster headaches are not treated with this medication.



Sumatriptan Nasal Spray is a topical aqueous suspension of microfine Sumatriptan BP 10 mg administered via a metering, atomizing spray pump to the nasal mucosa. Sumatriptan binds to human cloned 5 HT1B/1D receptors with a high affinity. Sumatriptan is thought to cure migraine headaches by acting as an agonist at the 5 HT1B/1D receptors on intracranial blood vessels and sensory nerves in the trigeminal system, resulting in cranial vessel constriction and suppression of pro-inflammatory neuropeptide release.



Route of administration: Nasal

  • Single-dose of 10 mg of nasal spray.
  • The maximum dose in a 24 hour period: 30 mg; separate doses by at least one hour or as directed by the physician.

Use in children and adolescents: Sumatriptan is not recommended for use in patients younger than 18 years of age.



How to use the Nasal Spray-

  • Shake the bottle gently and remove the dust cover.
  • Hold the spray with your forefinger and middle finger on either side of the nozzle and your thumb underneath the bottle. Press down until a fine spray appears. If using for the first time or if you have not used it for a week or more, press the nasal applicator several times until a fine moist comes out from the container.
  • Gently blow the nose to clear the nostrils.
  • Close one nostril and carefully insert the nasal applicator into the open nostril. Tilt your head forward slightly and keep the spray upright. Breathe in through your nose and while breathing in, press the white-collar of nasal applicator firmly down once to release a spray.
  • Breathe out through your mouth.
  • Repeat the above steps in the same/ other nostril for consecutive doses.

Cleaning: The nasal spray should be cleaned at least once a week. The procedures are as follows-

  • Remove the dust cover.
  • Gently pull off the nasal applicator.
  • Wash the applicator and dust cover in warm water.
  • Shake off the excess water and leave to dry in a normal place. Avoid to apply additional heat.
  • Gently push the applicator back on the top of the bottle and re-fix the dust cover.



With Ergot-Containing Drugs, Monoamine Oxidase-A Inhibitors, Other 5-HT1 Agonists, and Selective Serotonin Reuptake Inhibitors/Serotonin Norepinephrine Reuptake Inhibitors, Sumatriptan nasal spray is contraindicated.  Interactions with food and others: There is no contact with foods.



  • History of coronary artery disease or coronary vasospasm
  • Wolff-Parkinson-White syndrome or other cardiac accessory conduction pathway disorders
  • History of stroke, transient ischemic attack, or hemiplegic or basilar migraine
  • Peripheral vascular disease
  • Ischemic bowel disease
  • Uncontrolled hypertension
  • Recent (within 24 hours) use of another 5 HT1 agonist (e.g., another triptan) or of an ergotamine containing medication
  • Concurrent or recent (past 2 weeks) use of monoamine oxidase A inhibitor
  • Hypersensitivity to sumatriptan (angioedema and anaphylaxis seen)
  • Severe hepatic impairment


Side Effects

Unusual or unpleasant tongue taste; discomfort, burning, numbness, or tingling in the nose or throat; runny or stuffy nose after using the nasal treatment are all common adverse effects.

Anxiety, burning sensations, nasal cavity and throat discomfort, general feeling of illness or fatigue, and eyesight disturbances are all rare adverse effects.


Pregnancy & Lactation

There are no adequate and well-controlled studies in pregnant women and lactating mothers.


Precautions & Warnings

  • Prinzmetal’s angina and myocardial ischemia/infarction: In patients with multiple cardiovascular risk factors, a cardiac examination should be performed.
  • Arrhythmias: If this happens, stop taking Sumatriptan.
  • Pain, tightness, pressure, or heaviness in the chest, throat, neck, or jaw: In most cases, it is not linked to myocardial ischemia; however, those at high risk should be evaluated for coronary artery disease.
  • Stroke, cerebral hemorrhage, and subarachnoid hemorrhage: If this happens, stop taking Sumatriptan.
  • Ischemia and reactions in the gastrointestinal tract, as well as peripheral vasospastic reactions: If this happens, stop taking Sumatriptan.
  • Overuse of medication causes a headache: Detoxification might be required.Serotonin syndrome is a condition caused by a lack of serotonin If this happens, stop taking Sumatriptan.
  • Blood pressure elevation: A hypertensive crisis can happen at any time.
  • Reactions of hypersensitivity: Angioedema and anaphylaxis are possible side effects.
  • Seizures: In individuals with epilepsy or a decreased seizure threshold, use with caution.
  • Irritation on the spot: It’s possible that you’ll get a burning sensation and an unusual flavor.


Therapeutic Class

5-HT Agonists


Storage Conditions

The temperature should be kept between 20°C and 25°C. Keep out of the refrigerator and freezer. Before using, do not test.


Pharmaceutical Name

ACME Laboratories Ltd.