Steradin Hfa 250 MCG/PUFF

100110500800102

Steradin Hfa 250 MCG/PUFF

352.38৳ 

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Description

Indications of Steradin HFA 250 Inhaler

Beclometasone 50, 100, and 250 HFA inhalers are used for the prophylactic management of mild, moderate, or severe asthma in adults or children. Becrometa hand dipropionate, given by inhalation, provides prophylactic treatment for asthma. It has a lower incidence and severity of side effects than those observed when corticosteroids are administered systemically and provides effective anti-inflammatory effects on the lungs.

Mild asthma: Patients with regular symptoms who need bronchodilator asthma medication.

Moderate asthma: Patients with asthma instability or exacerbation despite prophylactic or bronchodilator monotherapy.

Severe asthma: Patients with severe chronic asthma and patients who rely on systemic corticosteroids for proper control of symptoms. Many patients who rely on systemic corticosteroids for proper control of symptoms significantly reduce their oral corticosteroid requirements or significantly reduce their oral corticosteroid requirements when converting to high-dose inhaled bichromate hand dipropionate. Can be eliminated.

Pharmacology of Steradin HFA 250 Inhaler

Beclomethasone dipropionate produces anti-inflammatory and vasoconstrictor effects. The mechanism underlying the anti-inflammatory effects of beclomethasone dipropionate is unknown. Corticosteroids have been shown to have multiple effects on many cell types (eg, mast cells, eosinophils, neutrophils, macrophages, and lymphocytes) and mediators (eg, histamine, eicosanoids, leukotrienes and cytokines) are involved in inflammation. The direct relationship between these findings and the effects of beclomethasone dipropionate on symptoms of allergic rhinitis is unknown.

Nasal mucosal biopsies obtained in clinical studies showed no histopathological changes when beclomethasone dipropionate was administered intranasally.

Beclomethasone dipropionate is a prodrug with a low binding affinity for the glucocorticoid receptor. It is hydrolyzed via esterase enzymes to its active metabolite, beclomethasone17monopropionate (B17MP), which has high local anti-inflammatory activity.

Dosage & Administration of Steradin HFA 250 Inhaler

Beclometasone dipropionate Inhaler is for oral inhalation use only. Patients should be given a starting dose of inhaled beclometasone dipropionate appropriate to the severity of their disease. The dose may then be adjusted until control is achieved, or reduced to the minimum effective dose according to individual response.

Adults (including the elderly): The usual starting dose is 200 micrograms twice a day. In more severe cases the starting dose may need to increase to 600 to 800 micrograms per day which may then be reduced when the patient’s asthma has stabilized. The total daily dose may be administered as two, three, or four divided doses

Children: 50 to 100 micrograms should be given two, three, or four times daily in accordance with the response. Alternatively, 100 micrograms or 200 micrograms twice daily should be given. The usual starting dose is 100 micrograms twice daily. Beclometasone 250 Inhaler is not recommended for children.

Beclometasone 250 HFA Inhaler: The usual starting dose is 200 micrograms twice a day. In more severe cases the starting dose may need to increase to 600 to 800 micrograms per day which may then be reduced when the patient’s asthma has stabilized. The total daily dose may be administered as two, three, or four divided doses.

There is no need to increase the dose in patients with hepatic or renal impairment.

Using an Inhaler seems simple, but most patients do not know how to use it in the right way. If the Inhaler is used in the wrong way, less medicine can reach the lungs. Correct and regular use of the Inhaler will prevent or lessen the severity of asthma attacks.

Following simple steps can help to use Inhaler effectively (According to “National Asthma Guidelines for Medical Practitioners” published by Asthma Association):

Take off the cap.

Shake the inhaler (at least six times) vigorously before each use.

If the inhaler is new or if it has not been used for a week or more, shake it well and release one puff into the air to make sure that it works.

Breathe out as fully as comfortably possible & hold the inhaler upright.

Place the actuator into the mouth between the teeth and close the lips around the mouthpiece.

While breathing deeply and slowly through the mouth, press down firmly and add fully to the canister to release medicine.

Remove the inhaler from the mouth. Continue holding your breath for at least 10 seconds or as long as it is comfortable.

If the doctor has prescribed more than one inhalation per treatment, wait 1 minute between puffs (inhalations). Shake the inhaler well and repeat steps 4 to 7.

After use, replace the cap on the mouthpiece. After each treatment, rinse your mouth with water.

Check your technique in front of a mirror from time to time, if you see a white mist during the inhalation, you may not have closed your lips properly around the mouthpiece, or you may not be breathing in as you press the can. This indicates a failure of the technique. If this happens, repeat the procedure from step 4 carefully.

Instructions for Cleaning Inhaler: Clean your Inhaler at least once a week. Remove the canister and rinse the plastic actuator and cap in warm water but do not put the metal canister into water. Dry the actuator and cap thoroughly and gently replace the metal canister into the actuator with a twisting motion. Put the cap on the mouthpiece.

Interaction of Steradin HFA 250 Inhaler

In general, in clinical trials, side effects are mainly related to the nasal mucosa. Adverse reactions reported in controlled clinical trials and long-term exposure trials in patients treated with a beclomethasone zillion inhaler are described below.

Nasal irritation and burning (11 per 100 patients) have been reported after the use of the

Beclomethasone Zipuropion acid-dotted nasal inhaler. In addition, occasional sneezing seizures (10 in 100 adult patients) occurred immediately after the use of the nasal inhaler. This symptom is well visible in children. A runny nose may occur occasionally (1 in 100 patients).

Contraindications

Hypersensitivity to any of the components. Special care is necessary for patients with active or quiescent pulmonary tuberculosis.

Side Effects of Steradin HFA 250 Inhaler

Systemic effects of inhaled corticosteroids may occur, especially at high doses prescribed for long periods of time. Possible systemic effects include Cushing’s syndrome, cushingoid features, and adrenal suppression, growth retardation in children and adolescents, decreased bone mineral density, cataracts, and increased intraocular pressure.

Pregnancy & Lactation

Caution should be exercised when administering salbutamol to patients with hyperthyroidism, cardiovascular disease, thromboembolic disorders, hypertension, and aneurysms. Hypokalemia with high doses of salbutamol may increase susceptibility to digitalis-induced arrhythmias. Rapid anaphylaxis may occur with prolonged use of high doses. Caution should be exercised when treating patients with diabetes or narrow-angle glaucoma and those on treatment with antihypertensive drugs.

Precautions & Warnings

The patient must instruct on the correct use of the inhaler and ensure that the drug for which the technique has been identified reaches the target area of ​​the lung. You should also be aware that beclometasone inhalers need to be used on a daily basis to achieve optimal results, even when asymptomatic.

Therapeutic Class

Respiratory corticosteroids

Storage Conditions

The Inhaler should be stored below 30° C, and protected from direct sunlight and heat. The canister should not be broken, punctured, or burnt, even when apparently empty. Keep away from eyes. Keep out of reach of children.

Pharmaceutical Name of Steradin HFA 250 Inhaler

ACI Limited

Generic of Steradin HFA 250 Inhaler

Beclomethasone Dipropionate