Indications of Spectazole 10 Cream

Econazole Nitrate is indicated for topical application-

• In the treatment of tinea pedis, tinea cruris, and tinea corporis caused by Trichophyton rubrum, Trichophyton mentagrophytes, Trichophyton tonsurans, Microsporum canis, Microsporum audouini, Microsporum gypseum, and Epidermophyton floccosum,
• In the treatment of cutaneous candidiasis, and in the treatment of tinea versicolor.

Pharmacology of Spectazole 10 Cream

Econazole Nitrate inhibits fungal oxidative enzymes, resulting in a deadly buildup of H2O2. They also inhibit the synthesis of ergosterol, a key component of the fungal cell wall.

Dosage & Administration of Spectazole 10 Cream

Econazole vaginal tablet: One tablet should be inserted deep into the vagina at bed time for three consecutive nights. Treatment should be continued even if menstruation occurs. Although a three night course of treatment is often sufficient longer courses are advisable for women with recurrent vaginal infections.

Econazole 30 gm cream: The supplied applicator should be filled with econazole cream and then inserted deep into the vagina at bedtime once or twice daily.

Econazole 10 gm cream: Apply sparingly to the affected area once or twice daily until improvement occurs.

Sufficient Econazole cream should be applied to cover affected areas once daily in patients with tinea pedis, tinea cruris, tinea corporis, and tinea versicolor, and twice daily (morning and evening) in patients with cutaneous candidiasis. Early relief of symptoms is experienced by the majority of patients and clinical improvement may be seen fairly soon after treatment is begun; however, candidal infections and tinea cruris and corporis should be treated for two weeks and tinea pedis for one month in order to reduce the possibility of recurrence. If a patient shows no clinical improvement after the treatment period, the diagnosis should be redetermined. Patients with tinea versicolor usually exhibit clinical and mycological clearing after two weeks of treatment.

Interaction of Spectazole 10 Cream

Prescription during pregnancy: It should not be prescribed unless there are strong grounds to do so. The smallest dose that is effective should be utilized. These medications are not advised during the third trimester of pregnancy.

Use in Lactation: Diclofenac may be identified in very minute amounts in breast milk, but no adverse effects on the infant are predicted.

Contraindications

Individuals who have exhibited hypersensitivity to any of the components of Econazole should avoid it.

Side Effects of Spectazole 10 Cream

During clinical studies, about 3% of patients treated with econazole nitrate 1% cream had side effects that were assumed to be caused by the medicine, with the most common ones being burning, itching, stinging, and erythema. A pruritic rash has also been described in one case.

Pregnancy & Lactation

In humans, intravaginal injection of econazole nitrate has not resulted in longer gestation or any severe reproductive consequences.

Pregnancy Classification C. Econazole nitrate should only be taken in the first trimester of pregnancy if the doctor believes it is necessary for the patient’s health. Only if plainly needed should the medicine be administered during the second and third trimesters of pregnancy.

The presence of econazole nitrate in human milk is unknown. When administering econazole nitrate to a nursing mother, exercise caution.

Precautions & Warnings

Econazole nitrate is not intended for use in the eyes. If a reaction that suggests sensitivity or chemical irritation occurs, the medicine should be stopped immediately. Only for external use. Econazole Nitrate Cream should not be applied to the eyes.

Therapeutic Class

Drugs used in Vaginal and Vulval conditions, Topical Antifungal preparations

Storage Conditions

Do not use it later than the date of expiry. Keep all medicine out of the reach of children. To be dispensed only on the prescription of a registered physician.

Pharmaceutical Name of Spectazole 10 Cream

Healthcare Pharmaceuticals Ltd

Generic of Spectazole 10 Cream

Econazole Nitrate