Sentix 1MG

105410022900102

Sentix 1MG

5.00৳ 

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In Stock

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Description

Generic

Flupentixol

 

Indications

Psychoses, Misery with or without uneasiness, Psychoses

 

Pharmacology

Flupentixol could be a thioxanthene antipsychotic that hinders dopamine-mediated effects by blocking postsynaptic dopamine receptors within the CNS.

 

Administration & Dosage

Oral-
Depression with or without anxiety:

  • Adult: Initially, 1 mg daily increased after 1 wk to 2 mg daily and then to a max of 3 mg daily, last dose should be given not later than 4 p.m. Doses >2 mg should be given in 2 divided doses. Discontinue treatment if there is no improvement within 1 wk of using the max dose.
  • Elderly: Initially, 0.5 mg daily increased after 1 wk to 1 mg daily with the last dose given not later than 4 p.m. Max: 2 mg daily in 2 divided doses.

Psychoses:

  • Adult: Initially, 3-9 mg bid, adjusted according to response. Max: 18 mg daily.
  • Elderly: Initial dose: ¼ or ½ of the usual initial dose.


Intramuscular-
Psychoses:

  • Adult: Initially, 20 mg (1 ml of a 2% oily solution) is given as test dose. After at least 7 days and depending on the response, subsequent doses of 20-40 mg may be given at intervals of 2-4 wk. Usual maintenance dose: 50 mg every 4 wk to 300 mg every 2 wk. Up to 400 mg wkly may be used in severe or resistant cases.
  • Elderly: Initial dose: ¼ or ½ of the usual initial dose.

 

Interaction

May potentiate the unfavorable impacts of drugs with antimuscarinic impacts e.g. TCAs. Decreased viability of levodopa. Increments unfavorable extrapyramidal side effects with dopamine enemies (metoclopramide and prochlorperazine).

 

Contraindications

Extreme touchinessGreatly volatile and overactive patients; madness; porphyria; coma; preexisting CNS sadness; bone-marrow supression; phaeochromocytoma.

 

Side Effect

Unbending nature, tremors, anxiety, tardive dyskinesia, sleep deprivation, dryness of mouth, wt pick up, sexual brokenness, galactorrhoea and menstrual disturbances. Potentially Lethal: Neuroleptic dangerous disorder (hyperthermia, hypertonicity of skeletal muscles, obviousness and autonomic anxious framework precariousness).

 

Pregnancy & Lactation

Category C: Either thinks about in creatures have uncovered unfavorable impacts on the baby (teratogenic or embryocidal or other) and there are no controlled thinks about in ladies or thinks about in ladies and creatures are not accessible. Drugs ought to be given as it were in case the potential advantage legitimizes the potential hazard to the hatchling

 

Precautions & Warnings

Patients with convulsive disarrangesprogressed hepatic, renal, CV or resp maladyerrands requiring mental sharpness; elderly (particularly with dementia), and weakened patients; neuroleptics with narcotic impact must be pulled back steadily; history of angle-closure glaucoma; urinary maintenance; prostatic hyperplasia; breast cancer, prolactin subordinate tumors; parkinsonism; myasthenia gravis; pregnancy; Dodge coordinate daylight.

 

Therapeutic Class

SSRIs & related anti-depressant drugs

 

Storage Conditions

Protect from light and moisture by storing below 30°C. Keep the medicine out of children’s reach.

 

Pharmaceutical Name

Eskayef Pharmaceuticals Ltd.