Generic

Levocetirizine Dihydrochloride

Indications

Levocetirizine is used to treat the symptoms of allergic diseases such as permanent allergic rhinitis, seasonal allergic rhinitis, and chronic idiopathic urticaria.

Pharmacology

Levocetirizine Dihydrochloride is included in this formulation. The active (Levo) isomer of cetirizine is levocetirizine. It is a novel nonsedating antihistamine with powerful antiallergic characteristics that is extremely effective and well tolerated. It has double the affinity for H1 receptors as cetirizine. Levocetirizine has a fast and long-acting mechanism, allowing for once-daily dosing.

Dosage & Administration

Adults and children 12 years of age and older: The recommended dose is 5 mg once daily.

Children 6 to 11 years of age: The recommended dose is 2.5 mg (1/2 tablet or 1 teaspoon oral solution) once daily.

Children 6 months to 5 years of age: The recommended dose is 1.25 mg (1/2 teaspoon oral solution) once daily.

Interaction

There are no known medication interactions with levocetirizine.

Contraindications

Hypersensitivity to levocetirizine, cetirizine, hydroxyzine, or its parent molecule. Levocetirizine should not be given to patients who have a significant renal impairment (creatinine clearance less than 10 ml/min).

Side Effects

Levocetirizine is generally well tolerated. A few adverse effects, including headache, dry mouth, tiredness, and skin rash, have been recorded seldom.

Pregnancy & Lactation

Category B Pregnancy. In pregnant women, there are no appropriate and well-controlled trials. Because animal reproduction studies are not always predictive of human response, levocetirizine should be administered only when obviously necessary during pregnancy. Because levocetirizine is secreted in breast milk, it is not advised that nursing women use it.

Precautions & Warnings

Patients with epilepsy and those at risk of convulsions and Renal dysfunction. Lactation and pregnancy.

Therapeutic Class

Non-sedating antihistamines

Storage Conditions

Store in a dry location at a temperature not exceeding 30°C. Keep out of direct sunlight.

Pharmaceutical Name

Incepta Pharmaceuticals Ltd