Indications of Rhinozol 0.1

Xylometazoline is used to treat nasal congestion, rhinitis, sinusitis, and headaches.

Nasal congestion is linked to tubal block and serous otitis media.

Pharmaceutical Name

ACME Laboratories Ltd

Pharmacology

Various etiologies, such as rhinosinusitis and allergic or non-allergic rhinitis, produce nasal congestion, resulting in congestion of the venous sinusoids lining the nasal mucosa. The activation of -adrenergic receptors causes the blood vessels of the nasal mucosa to constrict, allowing nasal airflow to resume. 1A- and 2B-adrenoceptors, which are the most abundantly expressed in the human nasal mucosa, may have the most essential function in nasal mucosa vasoconstriction. With affinity for 1A-, 2A-, 2C-, 1B-, and 1D-adrenoceptors, xylometazoline is a more selective agonist at 2B-adrenoceptors. Xylometazoline reduces nasal resistance and increases nasal airflow volume during inspiration and expiration. Xylometazoline exhibited a somewhat faster onset of effect than oxymetazoline, another imidazoline nasal decongestant, but having a similar duration of action. Subjects with nasal congestion reported relief of earache and sore throat in addition to nasal decongestion in one study; it is thought that oxymetazoline mediates this effect by causing vasoconstriction of the nasal mucosa, which contains the venous sinuses; nasal decongestion allows breathing through the nose, providing relief from sore throat caused by mouth breathing, which dries and irritates the throat; and nasal decongestion allows breathing through the nose, providing relief from

Dosage & Administration

Adults: Xylometazoline 0.1%: 2 or 3 drops in each nostril two to three times daily. Xylometazoline 0.1% should not be used for children under the age of 12 years.

Children 6 to 12 years of age: Xylometazoline 0.05%: 2 or 3 drops in each nostril two or three times daily.

Children less than 6 years of age: Xylometazoline 0.05%: 1 drop in each nostril two or three times daily.

Infants less than 3 months: Not to be used in infants less than 3 months.

Contraindications

Patients who have had a transsphenoidal hypophysectomy or surgery that exposes the dura mater should not use xylometazoline nasal drops. It’s also not recommended for people who are allergic to Xylometazoline. To avoid cross-infection, each Xylometazoline nasal drop should only be used by one person. Patients should not take decongestants for more than seven days in a row.

Side Effects

The following adverse effects have been reported on occasion:

• In the nose and throat, there is a burning sensation.
• Irritation on the spot
• Nausea and nasal mucosa that is dry.

Pregnancy & Lactation

Category C pregnancy. Xylometazoline is not recommended for usage during pregnancy. Only a doctor’s prescription should be followed when using Otrivin while nursing.

Precautions & Warnings

Xylometazoline Hydrochloride nasal drops for grown-ups (0.1%) ought to not be utilized for children underneath 12 a long time. Drops ought to not be utilized for long time in cases with constant rhinitis. Drawn out utilize of the drops may cause bounce back blockage and medicate initiated rhinitis.

Therapeutic Class

Nasal Anti-histamine preparations.

Storage Conditions

Protect yourself from the sun. Do not use the bottle for more than 28 days after opening it for hygiene concerns..

Generic Name of Rhinozol 0.1

Xylometazoline Hydrochloride