Reumacap 25 MG


Reumacap 25 MG


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Indomethacin is used to treat a variety of ailments.

Rheumatoid arthritis is a type of arthritis that affects the joints.

Ankylosing spondylitis is a type of arthritis that affects the spine.

Osteoarthritis is a type of arthritis that affects the joints (degenerative joint disease)

Gout is a type of non-articular rheumatism that occurs suddenly (bursitis, synovitis, tendinitis).



Indomethacin is a non-steroidal anti-inflammatory drug with antipyretic and analgesic effects. Numerous pharmacological studies have shown that indomethacin has strong anti-inflammatory, analgesic, and antipyretic effects. Unlike corticosteroids, the effects of indomethacin have nothing to do with the pituitary gland or the adrenal glands. Indomethacin is rapidly absorbed after oral administration and plasma peaks appear within 2 hours. About two-thirds of this amount is excreted in the urine and the rest is excreted in the feces. Approximately 90% of a single dose is excreted in 2448 hours. In a series of controlled clinical trials, indomethacin has been shown to be of significant value in the treatment of rheumatic diseases. It can reduce pain, reduce joint swelling and edema, and improve joint mobility.


Dosage & Administration

75 mg sustained-release capsule:

  • Rheumatoid arthritis, ankylosing spondylitis, and osteoarthritis (degenerative joint disease):The initial dose is 75 mg sustained-release capsule once daily. It severe then twice daily is required.
  • Acute attacks of gout: May control with a dose of 75 mg sustained-release capsule twice daily.
  • Acute non-articular rheumatism (bursitis, synovitis, tendinitis): 1-2 sustained-release capsule daily according to the severity of this case.

25 mg capsule:

  • Rheumatic diseases: 50-200 mg daily in divided doses
  • Acute gout: 150-200 mg daily in divided doses
  • Dysmenorrhea: up to 75 mg daily



It may interact with anticoagulants, Lithium, diuretics, antihypertensive drugs, diflunisal and sulfonylureas.



In patients with ulcers, gastritis, or active ulcerative colitis, indomethacin is contraindicated, and it should be used with caution in those who have a history of these conditions. In these circumstances, the use of Indomethacin suppositories is recommended. It is also not recommended for patients who have previously been hypersensitive.


Side Effects

During the first few weeks of therapy, you may experience headaches, mainly in the morning, and mild vertigo. These symptoms are usually temporary and go away with prolonged use or dose reduction. Mild psychic problems were also recorded in a few cases, although they went away after a few days of treatment. Large doses of the medicine often cause gastrointestinal responses such nausea, vomiting, diarrhoea, epigastric and abdominal discomfort, which go away as the dose is reduced. The pill should be taken promptly after meals, with an antacid if necessary, to reduce the frequency and severity of these side effects.


Precautions & Warnings

With psychiatric issues, epilepsy, or parkinsonism, Indomethacin pill should be used with caution, as the medicine may aggravate these diseases. Because clinical studies are currently lacking, it is not recommended for pregnant women. In newborns, indomethacin is only given if it is needed to help close a patent ductus arteriosus.


Therapeutic Class

Drugs for Osteoarthritis, Drugs used for Rheumatoid Arthritis, Non-steroidal Anti-inflammatory Drugs (NSAIDs)


Storage Conditions

Store in a cool and dry place protected from light. Keep out of the reach of children.


Pharmaceutical Name

Aristopharma Ltd.