Indications of Reef-DX Tablet

This is suitable for the treatment and prevention of osteoporosis, osteomalacia, hand and foot spasms, hypoparathyroidism and disorders of osteogenesis. It can also be used as a supplement to the diet of children, rickets, pregnancy and lactation, and elderly patients with insufficient calcium intake. Other indications include pancreatitis, phosphorus binders for chronic kidney failure, etc.

Pharmacology of Reef-DX Tablet

This is a preparation of calcium and vitamin D3, where calcium carbonate is obtained from coral sources. The chemical structure of coral calcium carbonate is very similar to the composition of human bones. Coral calcium is similar to other sources, but it ensures better absorption. Vitamin D3 helps to absorb calcium from the gastrointestinal tract and helps maintain calcium balance in the body.

Dosage & Administration of Reef-DX Tablet

One tablet once or twice daily with plenty of water or as directed by the physician. Taking in full stomach ensures better absorption.

Interactions of Reef-DX Tablet

Oral Calcium can reduce the absorption of tetracycline & fluoride preparations and minimum 3 hours time should be allowed between ingestion of these medications. Thiazide diuretics reduces the renal excretion of Calcium. Phenytoin, barbiturates, glucocorticoids may induce metabolism of Vitamin D3. Concomitant ingestion of certain foods like spinach, cereals, milk and its derivatives may reduce the intestinal uptake of Calcium.

Contraindications

Hypersensitivity to any of the components, hypocalcaemia resulting from overdose of Vitamin D3, hyperparathyroidism, bone metastases, severe renal insufficiency, severe hypercalciuria, renal calculi etc.

Side Effects of Reef-DX Tablet

Flatulence, diarrhoea, constipation, upper GI discomfort etc. are rare manifestation. Hypercalcaemia due to prolong use has rarely been reported.

Pregnancy & Lactation

This can be given to pregnant and lactating mothers as per recommendation of physician.

Precautions & Warnings

In presence of mild hypercalciuria, careful monitoring with reduction of dose may be needed. Plasma and serum Calcium level should be monitored in mild to moderate renal impairment and also in case of long-term use. Patients with renal stones or with such previous history should also take precautions.

Therapeutic Class

Specific mineral & vitamin combined preparations

Storage Conditions

Store at temperature of below 30°C, protect from light & moisture. Keep out of reach of children.

Pharmaceutical Name of Reef-DX Tablet

Healthcare Pharmaceuticals Ltd

Generic of Reef-DX Tablet

Calcium Carbonate [Coral source] + Vitamin D3