Generic

Povidone Iodine

Indications

Cream or ointment:

Therapeutic: As an adjunct to systemic treatment for the following indications

•  Primary or secondary local infection
•  Infected surgical incision
•  Infected pressure sores or stasis ulcer
•  Pyoderma
•  Secondary infection Dermatology
• 2 for burns, incisions, and other local injuries
•  for high nutrition, skin peeling during umbilical cord or circumcision
•  for abrasions, minor cuts, and wounds to prevent the development of infections and allow wounds to heal.

Solution:

•  is used to prevent and treat superficial infections, and remove bacteria from skin, mucous membranes, and high-nutrition procedures.
•  is used for seborrhea
•  is used for preoperative and postoperative cleaning and operating room and equipment cleaning
•  for surgery Preparing the surgical site, including the vagina
•  For disinfection of wounds, burns, lacerations, and abrasions
•  As a preventive anti-infective agent in home, hospital, and office procedures
•  Applying incisions after surgery to help prevent infection
•  In Oral candidiasis (thrush); bacterial and fungal infections of the skin, bedsores, and bruises
•  As a preoperative oral and throat swab
•  Mouth and mouthwash: It is a pleasant taste solution, used for:
•  It is used to treat acute infections of the mucous membranes of the oral cavity and pharynx.
•  is used for oral hygiene before, during, and after oral and dental surgery.

Surgical Scrub: It is a golden surfactant solution that forms a rich golden foam. Uses: As a disinfectant skin cleanser, it is used by surgeons and operating room staff to clean and clean before and after surgery and for patients before surgery Skin preparation

powder: It is used for topical application for the following indications: superficial wounds, small wounds, burns, abrasions, lacerations, treatment, and prevention of infections.

Pharmacology

Povidone Iodine is a mixture of iodine and povidone, an organic polymer. Povidone Iodine is preferable to conventional elemental iodine because of its polymerization. It extends iodine’s germicidal effect by progressively freeing elemental iodine. As a result, it is less hazardous than elemental iodine. Microbicidal action against Gram-positive and Gram-negative bacteria, protozoa, viruses, and fungi/yeasts is achieved quickly. It also has sporicidal properties. It’s the only microbicide with such a broad range of effects. It is non-staining, has a long-lasting germicidal effect, and may be used with soap, blood, serum, pus, mucosal secretions, and water.

Dosage & Administration

Cream or ointment:

For the treatment of infection: Apply once or twice daily or at dressing changes for a maximum of 14 days.

For the prevention of infection: Apply once or twice a week for as long as necessary. The affected skin should be cleaned and dried and can be covered with a dressing or bandage.

Solution: Apply full strength as often as needed as paint, spray, or wet soak. Maybe bandaged (where necessary).

Gargle & Mouthwash: Adults and children over 6 years of age: Use undiluted or diluted with an equal volume of warm water. Gargle or rinse with up to 10 mL for up to 30 seconds without swallowing. Repeat up to four times daily, for up to 14 consecutive days, or as advised by the Registered Dental Surgeon/Physician.

Surgical Scrub:

For Preoperative and Postoperative washing by Operating Personnel: Wet hands and forearms with water. Pour about 5 mL of Povidone Iodine Surgical Scrub on the palm of the hand and spread over both hands and forearms. Without adding more water, rub the Scrub thoroughly over all areas for about five minutes. Use a brush if desired. Clean thoroughly under fingernails. Add a little water and develop copious suds. Rinse thoroughly under running water. Complete the wash by scrubbing with another 5 mL of Povidone Iodine Surgical Scrub in the same way.

For Preoperative use on Patients: After the skin area is shaved, wet it with water. Apply Povidone Iodine Surgical Scrub (1 mL is sufficient to cover an area of 20-30 square inches), develop a lather, and scrub thoroughly for about five minutes. Rinse off with the aid of sterile gauze saturated with water.

For use in the Physician’s Office: Use for washing whenever a germicidal soap is required.

Powder: Apply a light dusting of powder to the affected area. When dry, this forms a protective antiseptic layer over the area treated. Or use as advised by the Registered Physician. There are no special dosage recommendations for children or elderly patients.

Interaction

Strong alkali, sodium thiosulphate, sodium metabisulphite, and thiomersal all interact with it. When used in conjunction with lithium medication, it has been demonstrated to have a hypothyroidism impact.

Contraindications

It has the potential to produce hypersensitive reactions. Patients with thyroid diseases (in particular nodular colloid goiter, endemic goiter, and Hashimoto’s thyroiditis) or those on lithium therapy should avoid using it on a regular basis. Because of the possibility of hepatic and renal damage in severely burned individuals, serum iodide levels should be checked. Povidone Iodine Powder is not recommended for use in significant cavities or in children under the age of two.

Side Effects

Povidone iodine can induce skin and mucous membrane irritation as well as hypersensitivity reactions. Systemic side effects such as metabolic acidosis, hypernatraemia, and renal function impairment may occur when povidone Iodine is applied to severe burns or significant patches of skin that are otherwise devoid of skin. Thyroid function tests may be affected.

Pregnancy & Lactation

Povidone Iodine Cream, Solution, and Powder are not suggested for usage during pregnancy due to the risk of fetal thyroid damage if enough iodine is absorbed. According to the American Academy of Pediatrics, using Povidone-Iodine is usually safe when breastfeeding. Please seek the advice of a licensed physician. Gargle and Mouthwash, as well as Surgical Scrub, should not be used on a regular basis by pregnant or nursing women.

Precautions & Warnings

Cream or ointment: If there is a deep or punctured wound or severe burn, see a registered physician. If redness, irritation, swelling, or pain persists or worsens, or infection occurs, discontinue use and consult a registered physician. Solution

: In preoperative preparation, avoid “bunching” under the patient. Prolonged contact with moist solutions may cause irritation or rare serious skin reactions. If there are deep wounds or severe stab wounds or burns, consult a registered physician. If redness, irritation, swelling, or pain persists or worsens, or infection occurs, discontinue use and consult a registered physician.

Mouthwash and mouthwash: Regular use should be avoided, as prolonged use can result in the absorption of large amounts of iodine. Do not use it for more than 14 days. If mouth ulcers or ulcers do not heal within 14 days, seek medical or dental advice. It also does not apply to children under 6 years of age. Patients also receiving lithium treatment should avoid regular use.

Surgical Scrub: For patients with pre-existing kidney failure, special care should be taken when applying regularly to damaged skin. Patients also receiving lithium treatment should avoid regular use. Platinum jewelry will permanently fade, it is recommended to remove it before using this product.

Powder: Care should be taken in use when it is known to be sensitive to iodine, although it does not generally react with povidone-iodine. Excess powder can be easily washed off with warm water. It must be used directly from the container. Don’t manage internally.

Therapeutic Class

Iodine compounds (Anti-septic Preparations)

Storage Conditions

Store below 25° C in a dry place, away from light. Keep out of the reach of children.

Pharmaceutical Name

Amico Laboratories Ltd.