Orabis 5 MG


Orabis 5 MG


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In Stock

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Indications of Orabis 5 Tablet

  • Bisoprolol is used to treat hypertension and angina.
  • Heart failure ranging from mild to severe


Pharmacology of Orabis 5 Tablet

The most selective ß1 blocker is Bisoprolol Hemifumarate. It has the highest affinity for the ß1 receptor of any beta-blocker currently on the market. Blocks the ß1 adrenergic receptor in the heart and vascular smooth muscle, lowering heart rate and cardiac output and lowering arterial blood pressure. In patients with non-ß1 selective ß1-blockers, ß-blockers can impact lipid metabolism, however Bisoprolol does not produce any changes in the cholesterol fraction, including the cardioprotective HDL-cholesterol, over long-term medication.


Dosage and Administration of Orabis 5 Tablet

Hypertension: The dose of Bisoprolol must be individualized to the needs of the patient. The usual starting dose is 5 mg once daily. In some patients, 2.5 mg may be an appropriate starting dose. If the antihypertensive effect of 5 mg is inadequate, the dose may be increased to 10 mg and then, if necessary, to 20 mg once daily.

Angina: Usually 10 mg once daily (5 mg may be adequate in some patients) max 20 mg daily.

Heart Failure: Initially 1.25 mg once daily (in the morning) for 1 week then, if well tolerated, increased to 2.5 mg once daily for 1 week, then 3.75 mg once daily for 1 week, then 5 mg once daily for 4 weeks, then- 7.5 mg once daily for 4 weeks, then 10 mg once daily maximum 10 mg daily.


Interaction of Orabis 5 Tablet

Other ß-blocking medications should not be taken with bisoprolol.



Right ventricular failure secondary to pulmonary hypertension and sinus bradycardia in individuals with cardiogenic shock, overt heart failure, second or third degree A-V block, and sinus bradycardia.


Side effects of Orabis 5 Tablet

It is possible to experience gastrointestinal disorders, bradycardia, hypotension, headache, fatigue, sleep disturbances, dizziness, vertigo, thrombocytopenia, vision disturbances, and alopecia.


Pregnancy & Lactation

Bisoprolol’s safety during pregnancy has yet to be determined. Lactation data isn’t available.


Precautions & Warnings

During long-term bisoprolol medication, renal, hepatic, and hematologic function should be monitored at regular intervals.


Therapeutic Class

Anti-adrenergic medicines (Beta blockers), pharmaceuticals that block beta-adrenoceptors, and beta-blockers


Storage Conditions

Store in a cool, dry location. Keep out of children’s reach.


Pharmaceutical Name of Orabis 5 Tablet

Ibn Sina Pharmaceuticals Ltd


Generic of Orabis 5 Tablet

Bisoprolol Hemifumarate