Nightus 3MG


Nightus 3MG


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Indications of Nightus Tablet

  • Lexotanil is indicated for anxiety, tension and other somatic or psychiatric complaints associated with the anxiety syndrome.
  • It can also be used as an adjunct for treatment of anxiety or excitation associated with psychiatric disorders, such as mood disorders or schizophrenia.
  • Benzodiazepines are only indicated when the disorder is severe, disabling or subjecting the individual to extreme distress.


Pharmacology of Nightus Tablet

Bromazepam is a very effective psychotropic medication. It selectively lowers stress and anxiety at lower doses. It has sedative and muscle-relaxant effects at larger doses. Bromazepam binds to the GABA-A receptor, causing it to alter shape and amplifying its inhibitory effects. Other neurotransmitters are unaffected.


Dosage & Administration of Nightus Tablet

Standard dosage

Average dosing for outpatient therapy: 1.5-3 mg up to three times daily. Severe cases, especially in hospital: 6-12 mg two or three times daily. These amounts are general recommendations, and dosage should be individually determined. Treatment of outpatients should begin with low doses, gradually increasing to the optimum level.Duration of Treatment

The duration of treatment should be as short as possible. The patient should be reassessed regularly and the need for continued treatment should be evaluated, especially in case the patient is symptom free. The overall treatment generally should not be more than 8-12 weeks, including a tapering off process. In certain cases extension beyond the maximum treatment period may be necessary, if so, it should not take place without re-evaluation of the patient’s status with special expertise. The patient should be checked regularly at the start of treatment in order to minimize the dosage
and/or the frequency of administration and to prevent overdose due to accumulation.


Interaction of Nightus Tablet

Bromazepam’s sedative effects may be increased when coupled with other centrally active medications. Antidepressants, hypnotics, opioids, antipsychotics, sedatives, antiepileptic medicines, sedative antihistamines, and anesthetics are examples of these medications. Cimetidine co-administration may increase the elimination half-life of bromazepam.



Lexotanil is contraindicated in patients with:
• known hypersensitivity to benzodiazepines or any of the excipients.
• severe respiratory insufficiency.
• severe hepatic impairment as benzodiazepines may precipitate hepatic encephalopathy
• sleep apnea syndrome


Side Effects of Nightus Tablet

Tiredness, sleepiness, muscular weakness, numbed muscle, decreased alertness, confusion, headache, ataxia, and other common side effects include fatigue, drowsiness, muscle weakness, numbed muscle, reduced alertness, confusion, headache, ataxia, and so on. These side effects are most common at the start of therapy and generally go away after a while. Anterograde amnesia may develop when therapeutic dosages are used.


Pregnancy & Lactation

Bromazepam’s safety during pregnancy has not been verified. Because bromazepam is secreted in breast milk, it should be avoided during pregnancy and breastfeeding.


Precautions & Warnings

The usage of benzodiazepines and benzodiazepine-like substances may result in physical and psychological dependency on these drugs. This dependency is dosage and treatment length dependent; it is also more prevalent in susceptible patients with a history of alcoholism. Once physical dependency has established, discontinuing therapy will result in withdrawal symptoms. Headache, muscular discomfort, severe anxiety, tension, disorientation, and irritability are some of the symptoms. Because the danger of withdrawal and rebound symptoms increases with sudden termination of therapy, it is suggested that the dosage be gradually reduced. Bromazepam is not indicated as a first-line therapy for insomnia induced by psychotic disease. Driving a car or using machinery should be done with caution.


Therapeutic Class

Benzodiazepine sedatives


Storage Conditions

Keep away from light and heat in a dry area. Keep out of children’s reach.


Pharmaceutical Name of Nightus Tablet

Beximco Pharmaceuticals Ltd


Generic of Nightus Tablet