Neurovan 75 MG

106410103301003

Neurovan 75 MG

18.00৳ 

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Description

Generic

Pregabalin

 

Indications

Pregabalin is prescribed to treat neuropathic pain caused by diabetic peripheral neuropathy.

  • Post-herpetic neuralgia treatment
  • Adult patients with partial-onset seizures may benefit from adjunctive therapy.
  • Fibromyalgia is treated in a variety of ways.
  • Neuropathic pain is a type of pain that occurs after a spinal cord injury.

 

Pharmacology

Pregabalin is a structural derivative of gamma-aminobutyric acid, an inhibitory neurotransmitter (GABA). It has no direct GABAA, GABAB, or benzodiazepine receptor binding. In central nervous system tissues, pregabalin binds to the alpha-2-delta site (an auxiliary subunit of voltage-gated calcium channels) with a high affinity. Pregabalin has a 90% oral bioavailability that is dose-independent. It is predominantly excreted from the systemic circulation as an unaltered medication by the kidneys, with a half-life of 6.3 hours in persons with normal renal function.

 

Dosage & Administration

Neuropathic pain associated with diabetic peripheral neuropathy: The maximum recommended dose of Pregabalin is 100 mg three times a day (300 mg/day) in patients with creatinine clearance of at least 60 mL/min. Dosing should begin at 50 mg three times a day (150 mg/day) and may be increased to 300 mg/day within 1 week based on efficacy and tolerability.

 

Interaction

Pregabalin has no noteworthy interactions with other antiepileptic medicines or oral contraceptives. The effects of ethanol and lorazepam may be amplified by pregabalin.

 

Contraindications

Patients who have a known hypersensitivity to Pregabalin or any of its components should avoid taking it.

 

Side Effects

The most common side effects include dizziness, somnolence, dry mouth, edema, blurred vision, weight gain and abnormal thinking.

 

Pregnancy & Lactation

Pregabalin has a pregnancy category of C. As a result, it should only be taken if the potential benefit outweighs the dangers to the fetus.

Pregabalin, like other medicines, can pass into breast milk, thus it should only be used in nursing mothers if the benefits clearly outweigh the risks.

 

Precautions & Warnings

Pregabalin withdrawal without tapering might cause insomnia, nausea, headaches, and diarrhea. As a result, rather than stopping abruptly, it should be tapered gradually over a minimum of one week. If you use Pregabalin, your creatinine kinase level may rise. If myopathy is detected or suspected, or if creatinine kinase levels are abnormally high, it should be stopped immediately.

 

Therapeutic Class

Adjunct anti-epileptic drugs

 

Storage Conditions

Do not store at temperatures above 30°C. Keep out of children’s reach.

 

Pharmaceutical Name

Aristopharma Ltd.