Description
Generic
Vitamin B1, B6 & B12
Indications
Neuralgin is indicated for the treatment of vitamin B1, B6, & B12 deficiency syndrome. It is also indicated for the supportive treatment of neuritis & non-inflammatory diseases of the nerves, eg. Diabetic neuropathy, Peripheral neuralgia, Lumbago, Myalgia, Optic neuritis, Sciatica, Facial neuralgia, Intercostal neuralgia, Spinal pain.
Pharmacology
Vitamin B1 changes over carbohydrates, greasy acids and amino acids into vitality, advances sound nerves, progresses disposition, fortifies the heart. Vitamin B6 shapes RBCs, makes a difference cells to create proteins, makes neurotransmitters e.g. serotonin and discharges put away shapes of vitality, makes a difference to avoid CVS infections and stroke, makes a difference to lift discouragement and facilitates a sleeping disorder. Vitamin B12 is fundamental for cell replication and vital for RBC generation, anticipates iron deficiency, makes a difference to anticipate sadness, diminishes nerve torment, deadness, shivering and brings down the hazard of heart diseases.
The vitamin fixings are ingested well in per verbal gathering. It is broadly dispersed to most tissues and shows up in breast drain. Inside the cell, thiamine is generally display as diphosphate. Thiamine isn’t put away to any appreciable degree within the body and sums in excess of the body’s necessities are excreted within the pee as unaltered thiamine or as metabolites. Pyridoxine, pyridoxal and pyridoxamine are promptly ingested from the GIT taking after verbal organization and are changed over to the dynamic shapes of pyridoxal phosphate an pyridoxamine phosphate. They are put away primarily in liver where there’s oxidation to 4-pyridoxic corrosive and other inert metabolites, which are excreted in pee. As the measurements increments, relatively more noteworthy sums are excreted unaltered within the pee.
Dosage and Administration
Tablet: 1-3 Tablets per day or as advised by the physician.
Injection: In severe (acute) cases- 1 injection IM daily until the acute symptoms subside or taken as advised bythe physician.In mild cases -1 injection IM 2-3 times per week. Ampoules are preferably injected intramuscularly.
Contradiction
Should not be used in the patients on Levodopa therapy and hypersensitivity to any of the active ingredients.
Side Effects
Generally well tolerated. However, a few allergic reactions may be seen.
Pregnancy & Lactation
Oral tablet form is recommended but due to presence of benzyl alcohol, injection is not recommended during pregnancy & lactation.
Precautions & Warnings
Cyanocobalamin should not be given before a diagnosis has been fully established because the possibility of masking symptoms of sub acute degeneration of the spinal cord.
Therapeutic Class
Specified combined vitamin preparations
Storage Conditions
Keep underneath 30°C temperature, absent from light & dampness. Keep out of the reach of children.
Pharmaceutical Name
Ibn Sina Pharmaceuticals Ltd.