Neural 0.5 MG

104910013700401

Neural 0.5 MG

4.25৳ 

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In Stock

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Description

Generic

Mecobalamin

 

Indications

Mecobalamin is indicated in-

  • Peripheral Neuropathies
  • Diabetic Neuropathy
  • Verteberal Syndrome
  • Nerve Compression Syndrome
  • Multiple sclerosis
  • Amyotrophic lateral sclerosis
  • Parkinson’s disease
  • Alzheimer’s disease
  • Diabetic retinopathy
  • Entrapment neuropathy
  • Drug induced neuropathy
  • Megaloblastic anemia due to Vitamin B12 deficiency

 

Pharmacology

Methylcobalamin is the neuroactive form of vitamin B12 and exists in the body as a water-soluble vitamin. It is a cofactor of methionine synthase and its function is to transfer methyl groups to regenerate methionine from homocysteine. In anemia, it increases red blood cell production by promoting nucleic acid synthesis in the bone marrow and promoting red blood cell maturation and division.

 

Dosage & Administration

Tablet: The usual adult dosage is 500 mcg tablet three times daily. The dosage should be adjusted according to the age of patient and the severity of symptoms.

Injection:

  • Peripheral neuropathies: The usual adult dosage is  500 mcg Mecobalamin administered intramuscularly or intravenously three times a week.The dosage should be adjusted according to the age of patient and the severity of symptoms.
  • Megaloblastic anemia: The usual adult dosage is  500 mcg Mecobalamin administered intramuscularly or intravenously three times a week. After about two months of administration, dosage should be changed to one ampoule equivalent to 500 mcg of Mecobalamin every one to three months as maintenance therapy

 

Interactions

Together with neomycin, aminosalicylic acid, H2 receptor blockers, and colchicine, it reduces gastrointestinal absorption. Oral contraceptives can reduce serum concentrations. The effect of parenteral chloramphenicol on anemia is reduced.

 

Contraindications

Allergic to any component of this product.

 

Side Effects

Methylcobalamin is generally well tolerated. However, some side effects can occur after taking mecobalamin, such as gastrointestinal upset (such as anorexia, nausea, or diarrhea) and a rash.

 

Pregnancy & Lactation

Not recommended during pregnancy & lactation.

 

Precautions & Warnings

The medicine should not be used for months if there is no response at all after its use for a certain period of time.

Therapeutic Class

Drugs for Megaloblastic Anemia

 

Storage Conditions

Oral: Store at room temperature. Protect from moisture and light.
Parenteral: Store at room temperature. Do not expose to direct light.

 

Pharmaceutical Name

Healthcare Pharmaceuticals Ltd.