Indications

The treatment of fungal infections where co-existing symptoms of inflammation e.g. itching, require rapid relief.

• All dermatomycoses are due to dermatophytes (e.g. Trichophyton species), molds, and other fungi.
• All dermatomycoses are due to yeasts (Candida species).
• Skin diseases showing secondary infection with these fungi
• The treatment of nappy rash where infection due to Candida albicans is present.

Pharmacology of Neosten HC 20 Cream

Clotrimazole inhibits the synthesis of ergosterol, leading to changes in the structure and function of the fungal cytoplasmic membrane. Hydrocortisone, a weak corticosteroid with both glucocorticoid and mineralocorticoid activity to a lesser extent, has antipyretic, antipruritic, antiemetic, and antiallergic effects.

Dosage & Administration of Neosten HC 20 Cream

Apply thinly and evenly to the affected area twice daily

Interaction of Neosten HC 20 Cream

May reduce the effectiveness of contraceptives.

Contraindications

It is contraindicated in patients with known hypersensitivity to any of the components of this preparation.

Side Effects of Neosten HC 20 Cream

Allergic reactions (eg, syncope, hives, dyspnea, hypotension), blisters, edema, discomfort/pain, erythema, peeling / peeling, irritation. Rarely, suppression of the hypothalamic-pituitary-adrenal axis, Cushing-like characteristics, weight gain/childhood growth retardation, glaucoma, HTN, hyperglycemia/diabetes, osteoporosis, cataracts, weight gain/obesity, decreased levels of endogenous cortisol, steroid withdrawal syndrome.

Pregnancy & Lactation

Pregnancy category: Not classified. The FDA has not yet classified this drug in a specific category for pregnant women.

Precautions & Warnings

In infants, the napkins may act as an occlusive dressing and increase absorption. Treatment should be for a maximum period of seven days.

Rarely local mild burning or irritation may be experienced. Hypersensitivity reactions may occur.

Therapeutic Class

Hydrocortisone & Combined preparations

Storage Conditions

Store in a dry area at a temperature of not more than 30°C. Light and dampness should be avoided. Keep out of children’s reach.

Pharmaceutical Name of Neosten HC 20 Cream

Beximco Pharmaceuticals Ltd

Generic of Neosten HC 20 Cream

Clotrimazole + Hydrocortisone