Neofloxin 5ML


Neofloxin 5ML


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Indications of Neofloxin Ophthalmic Solution

Ciprofloxacin 0.3 percent Eye/Ear Drops are used to treat infections caused by susceptible strains of the following bacteria in the following conditions:

Pseudomonas aeruginosa, Serratia marcescens, Staphylococcus aureus, Staphylococcus epidermidis, and Streptococcus pneumoniae are some of the bacteria that cause corneal ulcers.

Haemophilus influenza, Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus pneumonia, and Bacterial Conjunctivitis It’s also used to treat keratitis, kerato-conjunctivitis, blepharitis, blepharoconjunctivitis, and dacryocystitis, as well as to prevent ocular infections caused by Neisseria gonorrhea or Chlamydia trachomatis.

Pharmacology of Neofloxin Ophthalmic Solution

Ciprofloxacin is a broad-spectrum antibacterial drug that is administered intravenously. Ciprofloxacin’s bactericidal effect is due to the suppression of the topoisomerase II (DNA gyrase) and topoisomerase IV enzymes, which are necessary for bacterial DNA replication, transcription, repair, and recombination.

Dosage & Administration of Neofloxin Ophthalmic Solution

Corneal ulcers: The recommended dosage regimen for the treatment of corneal ulcers is two drops into the affected eye every 15 minutes for the first 6 hours and then two drops into the affected eye every 30 minutes for the remainder of the first day. On the second day, instill 2 drops in the affected eye hourly. On the third through the fourteenth day, place two drops in the affected eye every four hours. Treatment may be continued after 14 days if corneal re-epithelization has not occurred.

Bacterial conjunctivitis: The recommended dosage regimen for the treatment of bacterial conjunctivitis is one or two drops instilled into the conjunctival sac(s) every two hours while awake for two days and one or two drops every four hours while awake for the next five days.

Ear infections: For all infections, 2-3 drops every 2-3 hours initially, reducing the frequency of the instillation with control of infection. Treatment should be continued for at least 7 days.

Interaction of Neofloxin Ophthalmic Solution

Specific drug interaction studies have not been observed with ophthalmic Ciprofloxacin.


Hypersensitivity to quinolone group of antibacterials or any of the components of the formulation.

Side Effects of Neofloxin Ophthalmic Solution

Local burning or discomfort, itching, foreign body sensation, crystalline precipitates, lid margin crusting, conjunctival hyperemia, and a bad taste following administration. Photophobia and nausea may be reported.

Pregnancy & Lactation

Do not use unless the potential benefits outweigh the potential risk during pregnancy. It is not known whether excretion in human milk occurs following topical ophthalmic administration. Caution should be exercised in nursing mothers.

Precautions & Warnings

Prolonged ocular use of Ciprofloxacin may result in the overgrowth of non-susceptible organisms, including fungi. Ciprofloxacin should be discontinued at the first appearance of a skin rash or any other sign of hypersensitivity reaction.

Therapeutic Class

Aural Anti-bacterial preparations, Ophthalmic antibacterial drugs

Storage Conditions

Protect from light and moisture by storing in a cool, dry place below 30°C. Keep out of children’s reach.

Pharmaceutical Name of Neofloxin Ophthalmic Solution

Beximco Pharmaceuticals Ltd

Generic of Neofloxin Ophthalmic Solution