Nazin 10 ML


Nazin 10 ML


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Naphazoline + Zinc Sulfate



Noninfectious conjunctivitis (acute and chronic), nonspecific conjunctival irritation; also after effective treatment of bacterial and viral conjunctivitis. The tear ducts are irrigated.



Zinc ions, the active ingredient in zinc sulphate, have astringent (tissue-sealing) and antiseptic properties. Naphazoline constricts blood vessels and decreases conjunctival irritation and edema. Naphazoline, a benzylimidazoline compound, exerts this effect by binding directly to a-adrenergic receptor sites on unstriated muscle cells in blood arteries.


Dosage and Administration

Adults: 1 drop in the conjunctival sac, three to 4 times per day.

Children: Naphazoline nitrate and Zinc sulphate drops has not been studied in children. Generally, in children the dosage of vasoconstrictors should be low and selected with caution.



Naphazoline-containing items should not be used while using MAO-blockers or for the first 10 days after stopping the medication. Concurrent usage of tricyclic antidepressants may enhance the effects of Naphazoline.



Zinc sulphate, Naphazoline, and other substances cause hypersensitivity. Patients with narrow-angle glaucoma, dry eye, and notably keratoconjunctivitis sicca Sjogren’s syndrome should avoid Naphazoline & Zinc. Infants should not be given naphazoline or zinc.


Side Effects

In isolated circumstances, mydriasis and a modest increase in intraocular pressure can occur. After instillation, a small and transitory burning sensation may occur, but this has no bearing on the treatment’s efficacy. Long-term use could cause reactive redness in the eyes (rebound effect).

Systemic cardiovascular effects, such as hypertension and arrhythmia, may develop in extremely uncommon circumstances. Some people have experienced nonspecific weariness.


Pregnancy & Lactation

  • There are no controlled animal trials or research in pregnant women available for use during pregnancy.
  • Use during lactation: The effects of Naphazoline and Zinc during lactation have not been studied.


Precautions & Warnings

Naphazoline and Zinc should not be used in an uncontrolled manner for long periods of time. If there is no improvement after two days, the medication should be stopped and other therapeutic options considered. If you experience ocular discomfort or visual disruption while using Naphazoline with Zinc, you should stop taking it. Patients with a glaucoma tendency, as well as those with hypertension, cardiovascular illness, pheochromocytoma, aneurysm, hyperglycemia, and hyperthyroidism, should use caution.


Therapeutic Class

Ophthalmic Non-Steroid drugs


Pharmaceutical Name

Aristopharma Ltd