Generic

Moxifloxacin Hydrochloride + Dexamethasone

Indications

Moxifloxacin and Dexamethasone eye drops are used to treat infections caused by susceptible microorganisms in the eyes, as well as to avoid inflammation and bacterial infection after eye surgery.

Pharmacology

This eye drop contains Moxifloxacin, a fourth-generation fluoroquinolone, and Dexamethasone, a powerful corticosteroid. By inhibiting DNA gyrase and Topoisomerase IV, moxifloxacin prevents infection. By reducing the release of inflammatory mediators, dexamethasone effectively reduces inflammation.

Dosage & Administration

In the prevention of infection and post-surgical ocular inflammation: Instill 1 drop, 4 times a day, in the eye to be operated on, from 1 day before surgery until 15 days after surgery.

In patients undergoing cataract surgery: The day of surgery instill the medication immediately after eye surgery.

In patients undergoing LASIK refractive surgery: On the day of surgery instill the medication at least 15 minutes after ocular surgery.

In eye infections caused by susceptible microorganisms: Instill 1 drop, 4 times a day, for up to 7 days.

Contraindications

Quinolone hypersensitivity. Vaccinia, varicella, and other viral illnesses of the cornea and conjunctiva. Epithelial herpes simplex keratitis (dendritic keratitis), vaccinia, varicella, and other viral disorders of the cornea and conjunctiva. An eye infection caused by mycobacteria. Infections of the ocular structures caused by fungi. Glaucoma and disorders that cause corneal or sclera thinning.

Side Effects

The following one or more side effects may be observed: tendinopathy and tendon rupture, QT prolongation, hypersensitivity reactions, clostridium difficile-associated diarrhea, peripheral neuropathy, photosensitivity, phototoxicity, etc.

Pregnancy & Lactation

In pregnant women, there are no sufficient and well-controlled trials. Only use Moxifloxacin and Dexamethasone eye drops during pregnancy if the potential benefit outweighs the potential harm to the fetus. When using a combination of Moxifloxacin and Dexamethasone eye drops on a breastfeeding woman, use caution.

Precautions & Warnings

Only for ophthalmic use. The solution should not be injected directly into the anterior chamber of the eye or under the conjunctiva. Steroid use for a long time can cause ocular hypertension.

Therapeutic Class

Ophthalmic Steroid preparations.

Storage Conditions

Keep it cool, below 30°C, and out of direct sunlight. The contents of the container must be consumed within 28 days of opening, and they can be stored at room temperature up to 30°C. After 28 days, toss it out. Keep out of children’s reach.

Pharmaceutical Name

Incepta Pharmaceuticals Ltd.