Moxigen 5 ML


Moxigen 5 ML


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Moxifloxacin Hydrochloride


To treat bacterial conjunctivitis caused by the following pathogens, the ophthalmic solution is indicated:
Airborne gram-positive bacterium: Corynebacterium species, Micrococcus luteous, Staphylococcus aureus, Staphylococcus epidermidis, Staphylococcus haemolyticus, Streptococcus pneumonia, Streptococcus viridans group.
These microbes are Gram-negative aerobes, such as Haemophilus parainfluenza and Acinetobacter .
Chlamydia trachomatis is another microbe.


By inhibiting the topoisomerase II (DNA gyrase) and IV, Moxifloxacin is able to kill microbes and prevent them from reproducing in the first place Bacterial DNA replication, transcription, and repair depend on DNA gyrase which is a critical enzyme for this process. One of the most important functions of topoisomerase IV is the division of chromosomal DNA during cell division.

Dosage & Administration

Eye Drops One drop in the affected eye 3 times per day for 7 days.

Eye Ointment: It should be applied thinly and evenly to the affected eye three times a day for the first two days and for the next five days apply two times a day or as advised by the registered physician.


Studies on drug-drug interactions with Moxifloxacin Hydrochloride ophthalmic solution have not been undertaken to date. This means that Moxifloxacin is unlikely to affect the pharmacokinetics of medicines that are processed by these P450 isozymes.


Moxifloxacin, other quinolones, or any of the components in this drug are contraindicated in individuals with a history of hypersensitivity.

Side Effects

Acute conjunctivitis, poor visual acuity, dry eye (keratitis), discomfort, ocular hyperemia, ocular pain, and ocular pruritus were the most common ocular side effects observed. About 1 to 6 percent of participants experienced these complications. Fiber-increased cough, infection, and otitis media were among the non-ocular side effects recorded in the range of 1 to 4 percent.

Pregnancy & Lactation

When using Moxifloxacin Hydrochloride Ophthalmic Solution during pregnancy, the possible benefit should outweigh the potential danger to the fetus, as there are no sufficient and well-controlled studies in pregnant women. Despite the fact that moxifloxacin hasn’t been measured in human milk, it’s safe to assume that it’s excreted. When administering Moxifloxacin hydrochloride ophthalmic solution to a nursing mother, caution should be exercised.

Precautions & Warnings

This anti-long-term infective use can lead to an overgrowth of non-susceptible organisms, such as fungus In the event of a superinfection, discontinue the usage of the medication and seek alternate treatment. Magnification, such as slit lamp biomicroscopy, and fluorescein staining, should be used whenever clinical judgment requires. If a patient has signs and symptoms of bacterial conjunctivitis, he or she should be encouraged to refrain from wearing contact lenses.

Therapeutic Class

Ophthalmic antibacterial drugs

Storage Conditions

Store below 25°C. Do not freeze. Store in a cool and dry place, protected from light. Keep out of the reach of children. Do not touch the dropper tip to any surface as this may contaminate this preparation. Do not use it after one month of the first opening.

Pharmaceutical Name

General Pharmaceuticals Ltd.