Indications of Miclo 10 Ointment

Clobetasone preparations are indicated for the treatment of eczema and dermatitis of all kinds, including atopic eczema, photodermatitis, otitis externa, primary atopic dermatitis (including diaper rash), diaper rash, itchy nodules, seborrheic dermatitis and reactions to insect bites. Clobetasone can be used as a maintenance treatment between courses of any more active topical steroid.

Pharmacology of Miclo 10 Ointment

Clobetasone Butyrate is a topically active corticosteroid that offers an exceptional combination of activity and safety. It is more effective in treating eczema than 1% hydrocortisone or the less active synthetic steroid preparations commonly used. It has little effect on hypothalamic-pituitary-adrenal function. All topical corticosteroids can cause skin atrophy if abused. However, one study in animal and human models indicated that clobetasone butyrate was less likely to cause epidermal thinning than other topical steroids tested.

Dosage & Administration of Miclo 10 Ointment

Apply to the affected area up to four times a day until improvement occurs, when the frequency of application may be reduced.

Interaction of Miclo 10 Ointment

No potentially dangerous interactions have been reported. Potentially helpful interactions, none reported.

Contraindications

Pregnancy (in high doses), Presence of acute infection, Treatment of rosacea, Foot ulcers, Milia, Generalized plaque psoriasis. Children < 1-year-old.

Side Effects of Miclo 10 Ointment

Local atrophic changes; pigmentation changes and hyperpigmentation. Increased risk of infection. The infection may be covered up. Acute adrenal insufficiency. Children grow slowly. Cushingoid symptoms. Amenorrhea, hyperhidrosis, thinning of the skin

Pregnancy & Lactation

There is insufficient evidence of safety during pregnancy in humans. Administration of topical corticosteroids to pregnant animals may cause fetal development abnormalities, including cleft palate and intrauterine growth retardation. Therefore, there may be a very small risk of such effects in the fetus.

Precautions & Warnings

May be absorbed in amounts sufficient to cause systemic effects when applied topically to large areas of skin, to stretch marks, or under dressings. Peptic ulcer, osteoporosis, severe mental disorder, or neurosis. Do not use it indiscriminately in case of itching. CHF or hypertension. Diabetes mellitus, epilepsy, glaucoma, infectious diseases, ocular herpes simplex, chronic renal failure, and uremia. Inactive or suspected tuberculosis. Local treatment of eye disorders. The age. Long-term use on the face.

Therapeutic Class

Clobetasol / Clobetasone & Combined Preparations

Storage Conditions

Store below 30˚ C. Does not freeze. Protect from light.

Pharmaceutical Name of Miclo 10 Ointment

General Pharmaceuticals Ltd

Generic of Miclo 10 Ointment

Clobetasone Butyrate