Generic

Homatropine Hydrobromide

Indications

Homatropine Hydrobromide sterile Eye Drops are indicated for use as a mydriatic and cycloplegic agent.

Pharmacology

Homatropine is an antimuscarinic tertiary amine that blocks the response of the iris sphincter and regulatory ciliary muscle to cholinergic stimulation, causing dilation and loss of regulation.

Dosage & Administration

Mydriasis and cycloplegia for refraction:

• Adult: Instill 1 or 2 drops of 2% solution, or 1 drop of 5% solution immediately before the procedure, repeat at 5-10 minute intervals if necessary.
• Child: Instill 1 drop of 2% soln immediately before the procedure, repeat at 10-min intervals if necessary.

Uveitis:

• Adult: Instill 1-2 drops of 2% or 5% solution bid-tid up to every 3-4 hr as needed.
• Child: 3 mth- 2 yr: instill 1 drop of 0.5% soln once daily or on alternate days. >2 yr: instill 1 drop of 1% or 2% soln bid.

Interactions

Effects may be increased by drugs with antimuscarinic effects such as; some antihistamines; phenothiazines; antipsychotics; TCAs; MAOIs or parasympathomimetics.

Contraindications

Side Effects

Hypersensitivity may occur as conjunctivitis.

Pregnancy & Lactation

Use during pregnancy: There are no adequate and well-controlled studies in pregnant women. Matropin should only be used during pregnancy if the potential benefit poses a potential risk to the fetus.
Use during breastfeeding: It is not known whether somatropin is excreted in breast milk. Caution should be exercised when administering Matropin to nursing mothers.

Precautions & Warnings

Should be used with caution in patients with prostatic enlargement and in patients suffering from paralytic ileus or pyloric stenosis.

Therapeutic Class

Mydriatic and Cycloplegic agents

Storage Conditions

Store in a cool (below 30°C) and dry place, away from light. Keep out of the reach of children.

Pharmaceutical Name

Aristo vision