Indications of Lytex 15 ml Pediatric Drop

• Acute and chronic disease of respiratory tracts associated with viscid mucous including acute & chronic bronchitis.
• Productive cough
• Inflammatory diseases of the Rhinopharyngeal tract
• Asthmatic bronchitis, Bronchial asthma with thick expectoration –Bronchiectasis
• Chronic pneumonia

Pharmacology of Lytex 15 ml Pediatric Drop

Lytex 15 ml Pediatric Drop is the active metabolite of bromhexine and this metabolite has been shown to have a greater bronchial secretion effect than bromhexine. It improves the rheology of sputum through a hydration mechanism that leads to the liquefaction of mucus in the lumen of the respiratory tract, promoting coughing up mucus and reducing breathing difficulties. Stimulates alveolar cells to produce surfactant phospholipids, which helps reduce alveolar surface tension. It can also reduce bronchial hyperactivity. Due to its inhibitory effect on the production of cytokines and arachidonic acid metabolites, Ambroxol has anti-inflammatory properties. In COPD patients, it has traditionally improved airway patency.

Lytex 15 ml Pediatric Drop Dosage & Administration

Average daily dose (preferably after meal):

Pediatric Drops:

• 0-6 months: 0.5 ml 2 times a day
• 6-12 months: 1 ml 2 times a day
• 1-2 years: 1.25 ml 2 times a day

Syrup:

• 2-5 years: 2.5 ml (1/2 teaspoonful) 2-3 times a day
• 5-10 years: 5 ml (1 teaspoonful) 2-3 times a day
• 10 years and adults: 10 ml (2 teaspoonfuls) 3 times a day.

Sustained release capsule: Adults and children over 12 years old: 1 capsule once daily.

Interactions of Lytex 15 ml Pediatric Drop

Lytex 15 ml Pediatric Drop has no interaction with cardioactive glycosides, corticosteroids, bronchodilators, diuretics, and antibiotics (normally used in the treatment of bronchopulmonary infection). But Lytex 15 ml Pediatric Drop should not be taken simultaneously with antitussive (e.g. Codeine) because mucus, which has been liquefied by Ambroxol, might not be expectorated.

Contraindications of Lytex 15 ml Pediatric Drop

Contraindicated in known hypersensitivity to Ambroxol or Bromhexine.

Lytex 15 ml Pediatric Drop Side Effects

Gastrointestinal side effects like epigastric pain, and gastric fullness may occur occasionally. Rarely allergic responses such as eruption, urticaria, or angioneurotic edema may occur.

Pregnancy & Lactation

Pregnancy: Teratogenic and fetal toxicity studies have shown no harmful effect of Lytex 15 ml Pediatric Drop. However, it is advised not to use it during pregnancy, especially in the 1st trimester.

Lactation: Safety during Lactation has not yet been established.

Precautions & Warnings

Lytex 15 ml Pediatric Drop should be given cautiously to patients with gastric and duodenal ulceration or convulsive disorders. Patients with hepatic and renal insufficiency should take it with caution.

Therapeutic Class of Lytex 15 ml Pediatric Drop

Cough expectorants & mucolytics

Storage Conditions

Ibn Sina Pharmaceuticals Ltd

Generic

Ambroxol Hydrochloride