Losectil V 20MG


Losectil V 20MG


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In Stock






Omeprazole is demonstrated for the treatment of-

  • Gastric and duodenal ulcer
  • NSAID-associated duodenal and gastric ulcer
  •  As prophylaxis in patients with a history of NSAID-associated duodenal and gastric ulcer
  • Gastro-esophageal reflux disease
  • Long-term administration of corrosive reflux disease
  • Acid-related dyspepsia
  • Severe ulcerating reflux esophagitis
  • Prophylaxis of corrosive yearning amid common anesthesia Zollinger-Ellison syndrome
  • Helicobacter pylori-induced peptic ulcer.



Omeprazole, a substituted benzimidazole, is an inhibitor of gastric corrosive emission. It hinders gastric corrosive emission by blocking hydrogen-potassium-adenosine triphosphatase (H+/K+ ATPase) protein framework within the gastric parietal cell. After verbal organization, the onset of the antisecretory impact happens inside one hour, with the greatest impact happening inside two hours and restraint of discharge endures up to 72 hours. When the medicate is suspended, secretory movement returns slowly, over 3 to 5 days.


Dosage and Administration


  • Benign gastric and duodenal ulcer: 20 mg once day by day for 4 weeks in duodenal ulceration, 8 weeks in gastric ulceration; in extreme or repetitive cases, dosage to be expanded to 40 mg every dayupkeep dosage for repetitive duodenal ulcer, 20 mg once day by day; in anticipation of backslide in duodenal ulcer, 10-20 mg daily.
  • NSAID-associated duodenal or gastric ulcer: 20 mg once day by day for 4 weeks, proceeded for assist 4 weeks, on the off chance that not completely mended. 20 mg once day by day is utilized as prophylaxis in patients with a history of NSAID-associated duodenal or gastric ulcers.
  • Gastro-esophageal reflux malady20 mg once every day for 4 weeks, proceeded for encourage 4-8 weeks, on the off chance that not completely recuperated; 40 mg once day by day has been given for 8 weeks in gastro-esophageal reflux infectionhard-headed to other treatment; upkeep measurements is 20 mg once every day.
  • Long-term administration of corrosive reflux infection10-20 mg daily.
  • Acid-related dyspepsia: 10-20 mg once day by day for 2-4 weeks.
  • Prophylaxis of corrosive yearning: 40 mg on the going before evening, at that point 40 mg 2-6 hours some time recently surgery.
  • Zollinger-Ellison disorder: At first 60 mg once day by dayregular run 20-120 mg every day (In case every day measurements is more than 80 mg, 2 partitioned dosage ought to be used).
  • Helicobacter pylori annihilation regimen in peptic ulcer malady: Omeprazole is suggested at a dosage of 20 mg twice every day in affiliation with antimicrobial specialists as nitty gritty underneath: Amoxicillin 500 mg and Metronidazole 400 mg both three times a day for one week, or Clarithromycin 250 mg and Metronidazole 400 mg both twice a day for one week, or Amoxicillin 1 g and Clarithromycin 500 mg both twice a day for one week.
  • Paeditaric utilize in serious ulcerating reflux esophagitis (Child>1 year): In case body-weight 10-20 kg, 10-20 -mg once every day for 4-12 weeks; in the event that body-weight over 20 kg, 20-40 mg once every day for 4-12 weeks.

IV Injection-

  • Prophylaxis of corrosive yearningOmeprazole 40 mg to be given gradually (over a period of 5 minutes) as an intravenous infusion, one hour some time recently surgery.
  • Duodenal ulcer, gastric ulcer or reflux oesophagitis: In patients with duodenal ulcer, gastric ulcer or reflux oesophagitis where verbal pharmaceutical is unseemly, Omeprazole IV 40 mg once every day is recommended.
  • Zollinger- Ellison disorder (ZES): In patients with Zollinger-Ellison Disorder the suggested introductory measurements of Omeprazole given intravenously is 60 mg every day. Higher day by day dosages may be required and the dosage ought to be balanced independently. When dosages surpass 60 mg day by day, the measurements ought to be isolated & given twice day by day.



Omeprazole can draw out the end of diazepam, warfarin and phenytoin. So, diminishment of warfarin or phenytoin dosage may be vital when Omeprazole is included to the treatment. There’s no prove of an interaction of Omeprazole with theophylline, propranolol or stomach settling agents.



Omeprazole is contraindicated in patients with known touchiness to any of the components of the detailing.


Side Effect

Omeprazole is by and large well enduredSicknessstomach colic, paresthesia, tipsiness and cerebral pain have been expressed to be by and large mellow and transitory and not requiring a lessening in dose.


Pregnancy & Lactation

US FDA pregnancy category of Omeprazole is C. In any casecomes about from three planned epidemiological thinks about demonstrate no antagonistic impacts of Omeprazole on pregnancy or on the wellbeing of the fetus/newborn child. There’s no data accessible on the section of Omeprazole into breast drain or its impacts on the neonate. Breast-feeding ought tohence, be ceasedin case the utilize of Omeprazole is considered fundamental.


Precautions & Warnings

When gastric ulcer is suspected, the plausibility of gastric threat ought to be prohibited some time recently treatment with Omeprazole is foundations, as treatment may lighten the indications and delay determination.


Therapeutic Class

Proton Pump Inhibitor


Storage Conditions

Keep in a dry put absent from light and warm. Keep out of the reach of children.


Pharmaceutical Name

Eskayef Pharmaceuticals Ltd.