Description
Indications of Liptor 20
Liptor 20 is shown as an aide to slim down to diminish lifted add up to cholesterol, LDL cholesterol, apolipoprotein B (Apo-B) and triglycerides levels in taking after maladies when the reaction to slim down and other non-pharmacological measures is inadequate.
- To decrease add up to cholesterol and LDL cholesterol in patients with heterozygous and homozygous familial hypercholesterolaemia.
- To diminish raised cholesterol and triglycerides in quiet with blended dyslipidemia (Fredrickson Sort Ia and Ib).
- For the treatment of patients with raised serum triglyceride levels in hypertriglyceridaemia (Fredrickson Sort IV).
- For the treatment of patients with dysbetalipoproteinaemia (Fredrickson Sort III).
- To diminish cardiac ischaemic occasions in patients with asymptomatic or gentle to direct symptomatic coronary course malady with raised LDL-cholesterol level.
- To diminish add up to and LDL-cholesterol concentrations patients with hypercholesterolemia related with or exacerbated by diabetes mellitus or renal transplantation.
Pharmacology of Liptor 20
Atorvastatin may be a specific inhibitor of HMG-CoA reductase. This chemical is the rate-limiting protein dependable for the transformation of HMG-CoA to mevalonate, a forerunner of sterols, counting cholesterol. Atorvastatin brings down plasma cholesterol and lipoprotein levels by inhibiting HMG-CoA reductase and cholesterol blend within the liver and increments the number of hepatic LDL receptors on the cell surface for improved take-up and catabolism of LDL.
Dosage and Administration
Essential hypercholesterolaemia and combined hyperlipidaemia-
- Grown-ups: More often than not 10 mg once day by day; in the event that vital, maybe expanded at interims of at slightest 4 weeks to the max. 80 mg once daily.
- Child (10-18 a long time): At first 10 mg once day by day, expanded in case essential at interims of at slightest 4 weeks to the normal max. 20 mg once every day.
- Grown-ups: At first 10 mg every day, expanded at interims of at slightest 4 weeks to 40 mg once day by day; in the event that vital, advance expanded to the max. 80 mg once every day (or 40 mg once day by day combined with anion-exchange tar in heterozygous familial hypercholesterolaemia).
- Child (10-18 a long time): At first 10 mg once every day, expanded in case essential at interims of at slightest 4 weeks to the regular max. 80 mg once every day.
- Grown-ups: At first 10 mg once day by day balanced concurring to reaction.
Interaction of Liptor 20
The hazard of myopathy amid treatment with Atorvastatin is expanded with the concurrent organization of cyclosporin, fibric corrosive subsidiaries, erythromycin, azole antifungals and niacin. No clinically noteworthy intuitive were seen when Atorvastatin was managed with antihypertensives or hypoglycemic specialists. Patients ought to be closely observed in case Atorvastatin is included to digoxin, erythromycin, verbal contraceptives, colestipol, stomach settling agent and warfarin.
Contraindications
Side Effects of Liptor 20
Liptor 20 is for the most part well-tolerated. The foremost visit side impacts related to Liptor 20 are clogging, tooting, dyspepsia, stomach torment. Other side impacts incorporates contamination, cerebral pain, back torment, hasty, asthenia, arthralgia, myalgia.
Pregnancy & Lactation
Liptor 20 is contraindicated in pregnancy and whereas breastfeeding. Ladies of childbearing potential ought to utilize suitable prophylactic measures amid Atorvastatin treatment. In case the lady ended up pregnant while taking Liptor 20, it ought to be ceased.
Precautions & Warnings
Liver impacts: Liver work tests ought to be performed sometime recently the start of treatment and intermittently from that point. Atorvastatin ought to be utilized with caution in patients who devour significant amounts of liquor or have a history of liver illness. Liptor 20 treatment ought to be ceased in case uniquely raised CPK levels to happen or myopathy is analyzed or suspected.
Therapeutic Class
Other Anti-anginal & Anti-ischaemic drugs, Statins
Storage Conditions
Keep in a dry put absent from light and warm. Keep out of the reach of children.
Pharmaceutical Name of Liptor 20
ACME Laboratories Ltd
Generic of Liptor 20
Atorvastatin Calcium
