Description
Indications of Lindamax 25 ml Lotion
Clindamycin lotion is indicated in the treatment of acne vulgaris. Other uses of topical Clindamycin lotion are:
- Skin infections such as erythrasma caused by Corynebacterium minutissimum; rosacea, periorificial dermatitis, folliculitis, stasis, chronic lymphaedema and familial pemphigus.
- Dermal ulcers.
Pharmacology of Lindamax 25 ml Lotion
Clindamycin is a lincosamide antibiotic. It has bacteriostatic effect. It binds to the 50S subunit of bacterial ribosome and inhibits the early stage of protein synthesis. It is highly active against gram positive and anaerobic bacteria. It has activity against aerobic gram-positive cocci, including: Staphylococcus aureus, Staphylococcus epidermidis (penicillinase and non-penicillinase producing strains), Streptococci, Pneumococci. Anerobic gram-negative bacilli including; Bacteroids species, Fusobacterium species. Anaerobic gram-positove non-spore forming bacilli including: Propionibacterium species, Eubacterium species, Actinomyces species, Peptostreptococcus species, Microaerophillic streptococci, C. perferinges.
Dosage & Administration of Lindamax 25 ml Lotion
At first, wash the face or affected area gently with warm water or soap. When the skin is completely dried (about 30 minutes later) apply a thin film of Clindamycin lotion to the entire affected area twice daily. The Applied area should not be washed within 3 hours. Noticeable improvement is usually seen after about 6 weeks. However, 8 to 12 weeks of treatment may be required for maximum benefit. Eye, lip or nose contact should be avoided while applying Clindamycin lotion.
Interaction of Lindamax 25 ml Lotion
Clindamycin has been shown to have neuromuscular blocking properties that may enhance the action of other neuromuscular blocking agents. Therefore it should be used with caution in patients receiving such agents. Simultaneous use of other anti-acne or comedogenic cosmetic products should be avoided.
Contraindications
Clindamycin is contraindicated in patients with known history of hypersensitivity reactions to preparations containing Clindamycin, lincomycin, a history of regional enteritis or ulcerative colitis, or a history of antibiotic-associated colitis.
Side Effects of Lindamax 25 ml Lotion
Side effects are usually very rare which includes skin dryness, erythema, burning, peeling, oily skin, itching, diarrhea, colitis & GI disturbance.
Pregnancy & Lactation
Pregnancy category B. There are no adequate and well controlled studies in pregnant woman. This drug should be used during pregnancy only if clearly needed. It is not known whether Clindamycin is excreted in human milk following use of Clindamycin topical lotion.
However, orally and parenterally administered Clindamycin has been reported to appear in breast milk. Caution should be exercised when topical Clindamycin lotion is administered to a nursing woman.
Precautions & Warnings
Clindamycin lotion has an unpleasant taste and caution should be exercised when applying medication around the mouth. Clindamycin lotion may cause burning and irritation of the eye. In the event of accidental contact with sensitive surfaces (eye, abraded skin, mucous membranes), wash with copious amounts of cool tap water.
Therapeutic Class
Macrolides
Storage Conditions
Store in a cool (below 25°C) & dry place. Protect from light. Keep away from the reach of children. Do not freeze.
Pharmaceutical Name of Lindamax 25 ml Lotion
Eskayef Pharmaceuticals Ltd
