Description
Generic
Indications
As dietary supplement:
- Vitamin E deficiency resulting from impaired absorption
- Increased requirements due to diet rich in polyunsaturated fats
- For healthy hair & skin
- As an antioxidant
- Hemolytic anemia due to Vitamin E deficiency
Therapeutic use:
- Cardiovascular disease
- Heavy metal poisoning
- Hepatotoxin poisoning
- Hemolytic anemia
- Oxygen therapy
- In nutritional deficiency states.
Pharmacology
Vitamin E acts as an antioxidant within the body. Vitamin E ensures polyunsaturated greasy acids (which are components of cellular layer) and other oxygen-sensitive substances such as vitamin A & vitamin C from oxidation. In untimely neonates fractiousness, edema, thrombosis and hemolytic frailty may be caused due to vitamin E lack. Creatinuria, ceroid testimony, muscle shortcoming, diminished erythrocyte survival or expanded in vitro hemolysis by oxidizing specialists have been distinguished in grown-ups and children with moo serum tocopherol concentrations.
Administration & Dosage
Betterment of cardiovascular health: 400 IU-800 IU per day
Deficiency syndrome in adults: 200 IU-400 IU per day
Deficiency syndrome in children: 200 IU per day
Thalassemia: 800 IU per day
Sickle-cell anemia: 400 IU per day
Betterment of skin & hair: 200 IU-400 IU per day (Topical use is also established for beautification)
Chronic cold in adults: 200 IU per day
Interaction
Vitamin E may impair the absorption of Vitamin A & function of Vitamin K and potentiates the effect of Warfarin.
Contraindications
No known contraindications found.
Side Effects
Overdosage (>1 gm) have been associated with minor side effects, including hypertension, fatigue, diarrhea and myopathy.
Pregnancy & Lactation
Vitamin E is safe in pregnancy and lactation, when used as recommended doses. Higher doses are not established.
Precautions & Warnings
It may increase the risk of thrombosis in some patients, such as those taking estrogens.
Therapeutic Class
Herbal and Nutraceuticals, Vitamin-E Preparations
Storage Conditions
Protect from light and moisture by storing below 30°C. Keep the medicine out of children’s reach.
