Insulet R 10 ML


Insulet R 10 ML


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Insulin Human [Fast-Acting]



Treatment of all patients with sort 1 diabetes. Treatment of patients with sort 2 diabetes who are not satisfactorily controlled by slim down and/ or verbal hypoglycemic agents. For the beginning stabilization of diabetes in patients with diabetic ketoacidosis, hyperosmolar non-ketotic disorder and amid periods of push such as extreme contaminations and major surgery in diabetic patients. Treatment of gestational diabetes.



Affront Human (rDNA) is human affront made by recombinant DNA innovation. It has the same structure and work as normal affrontAffront controls the glucose digestion system and fortifies the ingestion and utilization of glucose by liver, muscle and fat tissue. It too brings down blood glucose by quickening glycogenesis and repressing gluconeogenesis. Insulin Human (rDNA) 30/70 & Affront Human (rDNA) 50/50 begin activity inside 30 minutes after infusion, reach crest level inside 2-8 hours and final almost 24 hours.


Administration & Dosage

The average range of total daily insulin requirement for maintenance therapy in type 1 diabetic patients lies between 0.5 and 1.0 IU/kg. In pre-pubertal children it usually varies from 0.7 to 1.0 IU/kg, whereas in insulin resistant cases, e.g. during puberty or due to obesity, the daily insulin requirement may be substantially higher. Initial dosages for type 2 diabetic patients are often lower, e.g. 0.3 to 0.6 IU/kg/day.

The dosage form, the dosage and the administration time of the insulin are different due to the individual differences of each patient. In addition, the dosage is also affected by food, working style and exercising intensity. Therefore, patients should use the insulin under doctor’s instruction.

Preparation before use:

  • Clean your hands.
  • Shake or rotate the vial gently to mix the solution uniformly and check if the insulin has the normal appearance.
  • In case of using a new vial, flip off the plastic protective cap and wipe the rubber plug with an alcohol swab.
  • Draw air into your syringe equal to the amount of insulin needed.
  • Puncture the needle into the vial and inject the air.
  • Turn the bottle and syringe upside down and withdraw correct dose of insulin into the syringe.
  • Before pulling out the needle, check if there are any bubbles remain in the syringe. If so, put the syringe upright and tap the syringe to discharge the air bubbles.Injection site:
    • Choose the area where skin is less tight, such as the upper arm, thigh, buttock or abdomen.
    • To avoid tissue damage, choose a site for each injection that is at least 1 cm from the previous injection site.

    Injection method:

    • Cleanse the skin with alcohol where the injection is to be made.
    • Put the needle in such a position as to form 45° angle with the skin.
    • Puncture the needle into skin and inject insulin.
    • Keep the needle under the skin for at least 6 seconds to make sure the entire dose is injected.
    • Pull the needle out and apply gentle pressure over the injected site for several seconds.
    • Do not rub the injection site.


When taking oral contraceptives, adrenal cortical hormone, thyroid hormone, and other drugs that cause blood glucose to rise, you may need to increase your Insulin dosage. When using hypoglycemic drugs such as salicylate, sulfanilamide, and other anti-depressants that cause a drop in blood glucose, the insulin dosage should be reduced.



Patients with hypoglycemia or who are allergic to insulin or any of the excipients.


Side Effect

Hypoglycemia is the most common side effect of insulin therapy, and symptoms of hypoglycemia can strike without warning. There have been a few reports of allergic reactions such as redness, swelling, and itching. It usually vanishes after a few days. In some cases, other factors, such as disinfectant or poor injection technique, may be to blame for the allergy rather than insulin.


Pregnancy & Lactation

Insulin treatment for diabetes is not restricted during pregnancy because insulin does not cross the placental barrier. The baby is not at risk from the mother’s insulin treatment.


Precautions & Warnings

Hyperglycemia can result from insufficient dosing or discontinuation, especially in people with type 1 diabetes. If the insulin dose is too high in comparison to the insulin requirement, hypoglycemia can occur. Hypoglycemia can be caused by skipping a meal or engaging in unplanned, strenuous physical activity.


Therapeutic Class

Insulin with a medium-term effect


Storage Conditions

Protect from light and moisture by storing below 30°C. Keep the medicine out of children’s reach.


Pharmaceutical Name

Aristopharma Ltd.