Generic

Silymarin [Milk thistle]

Indications

• Silymarin (Milk Thistle) is used to treat and prevent a variety of conditions, including liver disease (non-alcoholic & alcoholic)
• Cirrhosis of the liver (non-alcoholic & alcoholic)
• Infectious hepatitis is a type of hepatitis that is spread through the
• Hepatitis caused by drugs
• Diabetes mellitus causes liver damage.
• Narcotic toxicity is a term that refers to the toxicity of narcotics.
• Jaundice due to fatty liver

Pharmacology

The biologically active component is Silymarin, a flavonoid compound found in Silybum marianum, or Milk thistle. It promotes protein synthesis, antioxidant activity, anti-fibrotic activity, and possibly anti-inflammatory or immunomodulating actions while providing hepatocellular protection through toxin blocking at the membrane level.

Dosage and Administration

1 capsule 2 to 3 times daily or as directed by a physician.

Interaction

Lipid peroxidation has been reduced when silymarin and butyrophenones or phenothiazines are used together.

Contraindications

Patients who have a known hypersensitivity to silymarin should avoid it.

Side effects

In the recommended dose, it is well tolerated. A minor laxative effect may occur on occasion.

Pregnancy & Lactation

There is no evidence that Silymarin 70 mg or 140 mg can be used during pregnancy or lactation. As a result, if needed, Silymarin 70 mg or 140 mg should be used with caution and only as directed by a physician.

Therapeutic Class

Herbal and nutraceuticals, Cholagogues, Cholelitholytics, and Hepatic Protectors

Storage Conditions

Keep it cool and dry, away from light and moisture. Keep out of children’s reach.

Pharmaceutical Name

Drug International Ltd.