Indications of Gatigen 5 ml

This Sterile Eye Drops is shown for steroid responsive visual provocative conditions with involvement of microscopic organisms like blepharitis, scleritis, episcleritis, iritis, cyclitis, iridocyclitis, choroiditis, optic neuritis and incessant front uveitis, disciform and interstitial keratitis, unfavorably susceptible corneal marginal ulcers, corneal harm from chemical radiation or warm burns.

Pharmaceutical Name of Gatigen 5 ml

General Pharmaceuticals Ltd.

Pharmacology

Gatifloxacin’s antibacterial effect is due to its inhibition of DNA gyrase and topoisomerase IV. DNA gyrase is a necessary enzyme for the replication, transcription, and repair of bacterial DNA. Topoisomerase IV is an enzyme that is involved in chromosomal DNA partitioning during bacterial cell division. Fluoroquinolone antibiotics, such as gatifloxacin, have a distinct mode of action than aminoglycoside, macrolide, and tetracycline antibiotics. As a result, gatifloxacin may be effective against infections resistant to these antibiotics, while these drugs may be effective against gatifloxacin-resistant pathogens.There is no crossresistance between gatifloxacin and the medicines described above. Cross resistance between systemic gatifloxacin and various other fluoroquinolones has been documented. In vitro, gatifloxacin resistance arises by a series of mutations.

Dosage & Administration of Gatigen 5 ml

0.3% eye drops-

The recommended dosage regimen for the treatment of bacterial conjunctivitis is:

• Days 1 and 2: Instill one drop every two hours in the affected eye(s) while awake, up to 8 times daily.
• Days 3 through 7: Instill one drop up to 4 times daily while awake.

0.5% eye drops-

Patients 1 year of age or older: Instill one drop every two hours in the affected eye(s) while awake, up to 8 times on Day 1. Instill one drop two to four times daily in the affected eye(s) while awake on Days 2 through 7.

Interaction of Gatigen 5 ml

For the treatment of bronchitis, sinusitis, community-acquired pneumonia, and skin diseases (abscesses, wounds) caused by S. pneumoniae, H. influenzae, S. aureus, M. pneumoniae, C. pneumoniae, L. pneumophila, S. pyogenes

Contraindications

Typically contraindicated in epithelial herpes simplex keratitis (Dendritic keratitis), vaccinia, varicella, and in numerous other viral diseases of the conjunctiva and cornea. It is additionally contraindicated in mycobacterial disease of the eye, contagious illnesses of visual structures and in individuals hypersensitive to any of the components of the medication.

Side Effects of Gatigen 5 ml

Gentle burning, chemosis, redness may happen.

Pregnancy & Lactation

Utilize in pregnancy: There are no satisfactory and well-controlled considers in pregnant women. Gatifloxacin + Dexamethasone ought to be utilized amid pregnancy as it were on the off chance that the potential advantage justifies the potential hazard to the fetus.

Precautions & Warnings

For ophthalmic utilize as it were. On the off chance that the item is utilized for 10 days or more, intraocular weight ought to be monitored routinely.

Therapeutic Class

Ophthalmic steroid – antibiotic combined preparations

Storage Conditions

Store at room temperature. Ensure from light. Near the bottle promptly after utilize. Don’t utilize for longer than one month after opening the bottle.

Generic Name of Gatigen 5 ml

Gatifloxacin