Flutica Nasal .


Flutica Nasal .


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Flutica Nasal Spray is indicated for the treatment of symptoms of seasonal and perennial allergic rhinitis in adults and children above 2 years and for the prevention of recurrence of nasal polyps following surgical removal. Flutica Cream is indicated for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses such as eczema, psoriasis (excluding widespread plaque psoriasis), neurodermatitis, generalized erythroderma, insect bite reaction, and prickly heat.

Pharmaceutical Name

Aristopharma Ltd.


Fluticasone Furoate is a strong anti-inflammatory synthetic tri fluorinated corticosteroid. Fluticasone Furoate, like other corticosteroids, has a wide range of effects on a variety of cell types (mast cells, eosinophils, neutrophils, macrophages, lymphocytes) and mediators (histamine, eicosanoids, leukotrienes, cytokines) involved in inflammation.

Dosage and Administration

For intranasal use only. Adults and adolescents (12 years and over) The recommended starting dose is 2 sprays in each nostril once daily. Once adequate control of symptoms is achieved, a dose reduction to one spray in each nostril once daily can be effective for maintenance.

Children (2 to 11 years of age): The recommended starting dose is 1 spray in each nostril once daily.

Flutica Cream Apply a thin film of Flutica Cream to the affected skin areas once or twice daily. Rub in gently.


Fluticasone Furoate exposure may be increased by cytochrome P450 3A4 (CYP3A4) inhibitors. Ritonavir should not be taken with other medications. Coadministration of other powerful CYP3A4 inhibitors, such as ketoconazole, should be done with caution.

Patients should be told that the device must be primed before using it for the first time, as well as if the cap is left off, the device does not appear to be operating, or the nasal spray has not been used for 30 days or more. The nasal spray must be forcefully shaken for about 10 seconds with the cap on to prime the device. After that, the patient must press the button hard all the way around 6 times until a thin mist appears. The patient must shake the nasal spray firmly each time before using it once it has been primed.


Fluticasone Furoate is contraindicated for patients who have hypersensitivity to any components of this preparation. Side effects: The most common side effects are headache, epistaxis, pharyngolaryngeal pain, nasal ulceration, back pain, pyrexia, and cough.

Flutica Cream: This topical cream is contraindicated in those patients with a history of hypersensitivity to any of the components in the preparation.

Side Effects

The adverse reactions of Fluticasone Propionate are usually mild, and self-limiting, and consist primarily of pruritus, burning, hypertrichosis, irritation, etc. Apply a

thin film of Flutica Cream to the affected skin areas once or twice daily. Rub in gently.

Pregnancy & Lactation

Use in pregnancy: Pregnancy category C. There are no adequate and well-controlled studies on pregnant women. Fluticasone Furoate nasal spray should be used during pregnancy only if the potential benefit justifies the potential risk of the fetus.

Use in lactation: It is not known whether Fluticasone Furoate is excreted in human breast milk. However, since other corticosteroids have been detected in human milk, caution should be exercised when Fluticasone Furoate is administered to a nursing woman.

Pediatric use: The safety and effectiveness of Fluticasone Furoate in children younger than 2 years have not been established.

Geriatric use: In general, dose selection for the elderly patient should be cautious, keeping in mind the greater frequency of decreased hepatic, renal, or cardiac function, and of concomitant disease or other drug therapy.

Use in hepatic impairment: Use Fluticasone Furoate with caution in patients with severe hepatic impairment.

Use in renal impairment: No dosage adjustment is required in patients with renal impairment.

Pregnancy Category C. Caution should be exercised when this preparation is administered to a nursing woman.

Precautions & Warnings

Patients taking Fluticasone Furoate nasal spray should be periodically monitored for signs of adverse effects on the nasal mucosa such as epistaxis, nasal ulceration, and impaired wound healing. Avoid using the drug in patients with recent nasal ulcers, nasal surgery, or nasal trauma. Closely monitor patients with a history of increased intraocular pressure, glaucoma, and hypersensitivity reactions (including anaphylaxis, angioedema, rash, and urticaria). Besides, potential worsening of existing fungal, bacterial, viral, or parasitic infections or ocular herpes simplex, hypercorticism, and growth retardation may occur after the administration of Fluticasone Furoate nasal spray.

Flutica Cream: Fluticasone Propionate should not be used in the presence of preexisting skin atrophy and should not be used where the infection is present at the treatment site. It should not be used in the treatment of rosacea and perioral dermatitis.

Therapeutic Class

Nasal Steroid Preparations

Storage Conditions

Store below 30° C, Keep in at a dry place & protect from light.


Fluticasone Furoate