Indications of Fix-A Capsule

Cefixime is indicated in the treatment of the following infections when caused by the susceptible strains of the designated microorganisms:

• Uncomplicated urinary tract infections caused by Escherichia coli and Proteus mirabilis.
• Otitis Media caused by Hemophilus influenzae, Moraxella catarrhalis and Streptococcus pyogenes.
• Pharyngitis and tonsillitis caused by Streptococcus pyogenes.
• Acute bronchitis and acute exacerbations of chronic bronchitis caused by Streptococcus pneumoniae and Hemophilus influenza.
• Uncomplicated gonorrhea (cervical/urethral) caused by Neisseria gonorrhoeae.

Pharmaceutical Name of Fix-A Capsule

ACME Laboratories Ltd.

Pharmacology

Cefixime is a third-era semisynthetic cephalosporin anti-toxin for the oral organization. It is bactericidal against a wide range of gram-positive and gram-negative microbes at effectively reachable plasma focus. It kills microbes by meddling in the union of bacterial cell dividers. It is exceptionally steady within the sight of the Beta-lactamase compound. Thus, numerous organic entities impervious to penicillin and a few cephalosporins because of the presence of beta-lactamases, might be vulnerable to Cefixime. Retention of it is about 40% to half whether directed with or without food.

Dosage & Administration of Fix-A Capsule

The usual course of treatment is 7 days. This may be continued for up to 14 days depending on the severity of the infection.

Adult and children over 12 years: The recommended adult dose is 200-400 mg (1 to 2 capsules) daily, given either as a single dose or in two divided doses. For the treatment of uncomplicated cervical/urethral gonococcal infections, a single oral dose of Cefixime 400 mg is recommended.

Children (6 months or older): Usually 8 mg/kg/day given as a single dose or in two divided doses or may be given as follows

• ½-1 year: 75 mg daily.
• 1-4 years: 100 mg daily.
• 5-10 years: 200 mg daily.
• 11-12 years: 300 mg daily
• In typhoid fever, the dosage should be 10 mg/kg/day for 14 days.

Children (under 6 months): The safety and efficacy of Cefixime have not been established in children aged less than 6 months.

Interaction of Fix-A Capsule

Carbamazepine: Taking these drugs together raises the carbamazepine level. Concurrent use of warfarin and other anticoagulants raises prothrombin time.

Contraindications

It’s not recommended if you’re allergic to Cefixime or other cephalosporins. Pregnancy & Lactation.

Side Effects of Fix-A Capsule

The medication is for the most part all around endured. The most regular incidental effects are looseness of the bowels and stool changes; which have been all the more generally connected with higher dosages. Opposite incidental effects are sickness, stomach torment, dyspepsia, heaving, tooting, migraine, and wooziness. Hypersensitivities as rash, pruritus, urticaria, drug fever, and arthralgia have been accounted for. These responses for the most part died endless supply of treatment.

Pregnancy & Lactation

There are, however, no adequate and well-controlled studies in pregnant women. Because animal reproduction studies are not always predictive of human response, this drug should be used during pregnancy only if clearly needed. It is not known that Cefixime is excreted in human milk. So, caution should be exercised when Cefixime is administered to a nursing woman.

Precautions & Warnings

The drug should be prescribed with caution in individuals with a history of gastrointestinal disease, particularly colitis. The drug should be given with caution in patients with marked impaired renal function as well as those undergoing continuous ambulatory peritoneal dialysis and hemodialysis. Dosage adjustment is only necessary in severe renal failure (creatinine clearance < 20 ml/min), in that case, a dose of 200 mg once daily should not be exceeded.

Therapeutic Class

Third Generation Cephalosporins.

Storage Conditions

Keep below 30ºC temperature, protected from light & moisture. Keep out of the reach of children.

Generic of Fix-A Capsule

Cefixime Trihydrate.