Indications of Feripon 500mg Tablet

Iron overload in patients with thalassemia.

Pharmacology of Feripon 500mg Tablet

Deferiprone is a chelating agent that has an affinity for ferric ions (iron III). The combination of deferiprone and ferric ions forms a neutral 3: 1 complex (deferiprone: iron), which is stable over a wide pH range. Compared to iron, deferiprone has a lower binding affinity for other metals such as copper, aluminum, and zinc.

Feripon 500mg Tablet Dosage & Administration

Adult: 25 mg/kg tid. Doses >100 mg/kg daily are not recommended.
Child: >6 yr: 25 mg/kg tid.

May be taken with or without food.

Interaction

Avoid using deferiprone with antacids containing aluminum because it can chelate trivalent metal ions.

Contraindications

Agranulocytosis, pregnancy and lactation.

Feripon 500mg Tablet Side Effects

Musculoskeletal and joint pain; GI disturbances; red-brown discoloration of urine; transient liver enzyme abnormalities; zinc deficiency; neutropenia and agranulocytosis.

Pregnancy & Lactation

Pregnancy category D. There is positive evidence of risks to the human fetus, but despite the risks, the benefits of use in pregnant women may be acceptable (for example, if the drug is needed in a life-threatening situation or for use where drugs Safer can not be used Serious diseases) use or ineffective).

Precautions & Warnings

Hepatic and renal impairment. Neutropenia, monitor neutrophil count wkly and discontinue treatment if neutropenia develops. Limited experience in children 6-10 yr.

Therapeutic Class

Antidote preparations

Storage Conditions

Store below 30° C.

Pharmaceutical Name

Drug International Ltd

Generic

Deferiprone