Exovate 10GM


Exovate 10GM


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Indications of Exovate 10 Cream

Clobetasol Propionate is demonstrated for grown-ups, elderly and children over 1 year in taking after dermatoses. Psoriasis (barring far reaching plaque psoriasis) Recalcitrant dermatoses Lichen planus Discoid lupus erythematosus Other skin conditions which don’t react palatably to less strong steroids.


Pharmacology of Exovate 10 Cream

Clobetasol Propionate may be a exceptionally strong topical corticosteroid. It has anti-inflammatory, antipruritic and vasoconstrictive properties. It appears anti-inflammatory movement by means of numerous components to hinder late stage unfavorably susceptible responses. It diminishes the thickness of pole cells, chemotaxis and enactment of eosinophils. It moreover decreases cytokine generation and represses the digestion system of arachidonic acid.


Administration & Dosage of Exovate 10 Cream

Adults, elderly and children over 1 year: Apply a thin layer of Clobetasol Propionate Cream or Ointment to the affected skin areas twice daily and rub in gently and completely. Repeated short courses of Clobetasol Propionate may be used to control exacerbations. In more resistant lesions, especially where there is hyperkeratosis, the effect of Clobetasol can be enhanced, if necessary, by occluding the treatment area with polythene film. Overnight occlusion only is usually adequate to bring about a satisfactory response. Clobetasol Propionate is super-high potency topical corticosteroids; therefore, treatment should be limited to 2 consecutive weeks. The maximum weekly dose should not be exceeded 50 gm/week. In case of children, courses should be limited if possible to five days and reviewed weekly.Route of administration: Cutaneous. Creams are especially appropriate for moist or weeping surfaces. Ointments are especially appropriate for dry, lichenified or scaly lesions.


Interaction of Exovate 10 Cream

Co-administered drugs that can restrain CYP3A4 (eg ritonavir, itraconazole) have been appeared to hinder the digestion system of corticosteroids driving to expanded systemic presentation.



It is contraindicated in quiet with touchiness to any component of the planning. It ought to not be utilized in rosacea, skin break out vulgaris, perioral dermatitis, perianal and genital pruritus, pruritus without irritation, untreated cutaneous diseases.


Side Effect of Exovate 10 Cream

The foremost detailed side impacts are burning and stinging sensation. Less visit antagonistic responses are tingling, skin decaysplitting and fissuring of the skin. Cushing disorder has been detailed in newborn children and grown-ups as a result of drawn out utilize of topical Clobetasol Propionate definitions.


Pregnancy & Lactation

There are restricted information from the utilize of Clobetasol Propionate cream in pregnant ladies. Topical organization of corticosteroids to pregnant creatures can cause anomalies of fetal improvement. The pertinence of this finding to people has not been built upIn any case, the organization of Clobetasol Propionate Cream amid pregnancy and lactation ought to as it were be considered in the event that the anticipated advantage to the mother exceeds the conceivable dangers of treatment. It is obscure whether this sedate is excreted in human drainSince numerous drugs are excreted in human drain, caution ought to be worked out when Clobetasol Propionate Cream is managed to a nursing lady.


Precautions & Warnings

In case of utilizing occlusive dressings, the skin ought to be cleansed some time recently a new dressing is connected. Topical corticosteroids ought to be utilized with caution in psoriasis as bounce back backslides, and advancement of neighborhood or systemic poisonous quality due to disabled obstruction work of the skin may happenOn the off chance that utilized on the confront, treatment ought to be restricted to 5 days. When Clobetasol Propionate utilized on eyelids, care ought to be taken to maintain a strategic distance from the eyes as cataract and glaucoma might result from rehashed introduction.


Therapeutic Class

Other Topical corticosteroids


Storage Conditions

Protect from light and moisture by storing below 30°C. Keep the medicine out of children’s reach.


Pharmaceutical Name of Exovate 10 Cream

Beximco Pharmaceuticals Ltd

Generic of Exovate 10 Cream

Clobetasol Propionate