Exovate 10GM


Exovate 10GM


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Clobetasol Propionate is demonstrated for grown-ups, the elderly, and children over 1 year in taking after dermatoses. Psoriasis (barring far-reaching plaque psoriasis) Recalcitrant dermatoses Lichen planus Discoid lupus erythematosus Other skin conditions which don’t react palatably to less strong steroids.

Pharmacology of Exovate 10 Ointment

Clobetasol Propionate may be an exceptionally strong topical corticosteroid. It has anti-inflammatory, antipruritic, and vasoconstrictive properties. It appears anti-inflammatory movement by means of numerous components to hinder late-stage unfavorably susceptible responses. It diminishes the thickness of pole cells, chemotaxis, and enactment of eosinophils. It moreover decreases cytokine generation and represses the digestion system of arachidonic acid.

Administration & Dosage of Exovate 10 Ointment

Adults, elderly, and children over 1 year: Apply a thin layer of Clobetasol Propionate Cream or Ointment to the affected skin areas twice daily and rub in gently and completely. Repeated short courses of Clobetasol Propionate may be used to control exacerbations. In more resistant lesions, especially where there is hyperkeratosis, the effect of Clobetasol can be enhanced, if necessary, by occluding the treatment area with polythene film. Overnight occlusion only is usually adequate to bring about a satisfactory response. Clobetasol Propionate is a super-high potency topical corticosteroid; therefore, treatment should be limited to 2 consecutive weeks. The maximum weekly dose should not be exceeded 50 gm/week. In the case of children, courses should be limited if possible to five days and reviewed weekly. Route of administration: Cutaneous. Creams are especially appropriate for moist or weeping surfaces. Ointments are especially appropriate for dry, lichenified, or scaly lesions.

Interaction of Exovate 10 Ointment

Co-administered drugs that can restrain CYP3A4 (eg ritonavir, itraconazole) have appeared to hinder the digestion system of corticosteroids driving expanded systemic presentation.


It is contraindicated in quiet with touchiness to any component of the planning. It ought to not be utilized in rosacea, skin break-out vulgaris, perioral dermatitis, perianal and genital pruritus, pruritus without irritation, and untreated cutaneous diseases.

Side Effect of Exovate 10 Ointment

The foremost detailed side impacts are burning and stinging sensations. Less visit antagonistic responses are tingling, skin decaysplitting, and fissuring of the skin. Cushing disorder has been detailed in newborn children and grown-ups as a result of drawn-out utilization of topical Clobetasol Propionate definitions.

Pregnancy & Lactation

There is restricted information on the utilization of Clobetasol Propionate cream in pregnant ladies. Topical organization of corticosteroids to pregnant creatures can cause anomalies of fetal improvement. The pertinence of this finding to people has not been built upIn any case, the organization of Clobetasol Propionate Cream amid pregnancy and lactation ought to as it was being considered in the event that the anticipated advantage to the mother exceeds the conceivable dangers of treatment. It is obscure whether this sedate is excreted in the human drainSince numerous drugs are excreted in the human drain, caution ought to be worked out when Clobetasol Propionate Cream is managed by a nursing lady.

Precautions & Warnings

In the case of utilizing occlusive dressings, the skin ought to be cleansed sometime recently a new dressing is connected. Topical corticosteroids ought to be utilized with caution in psoriasis as bounce-back backslides, and advancement of the neighborhood or systemic poisonous quality due to disabled obstruction work of the skin may happenOn the off chance that utilized on the confront, treatment ought to be restricted to 5 days. When Clobetasol Propionate is utilized on eyelids, care ought to be taken to maintain a strategic distance from the eyes as cataracts and glaucoma might result from the rehashed introduction.

Therapeutic Class

Other Topical corticosteroids

Storage Conditions

Protect from light and moisture by storing below 30°C. Keep the medicine out of children’s reach.

Pharmaceutical Name of Exovate 10 Ointment

Beximco Pharmaceuticals Ltd

Generic of Exovate 10 Ointment

Clobetasol Propionate