Description
Generic
Indications
High-impact Gram-Positive bacteria- Corynebacterium species Staphylococcus oureus Staphylococcus epidermidis Streptococcus pneumoniae Streptococcus (Bunches C/F) Streptococcus (Gather G) Streptococcus viridons group Aerobic Gram-Negative bacteria- Acinetobocter Iwoffii Haemophilus influenzae Serrotia morcescens Levofloxacin too gives a promising treatment for other visual contaminations counting– Bacterial corneal ulcer, Blepharitis, Hordeolum & Perioperative condition.
Pharmacology
Levofloxacin eye drops may be a sterile topical ophthalmic arrangement. It could be a manufactured, wide range, third era fluoroquinolone bactericidal anti-microbial, which dynamic against a wide range of Gram-positive & Gram-negative visual pathogens. It capacities by repressing bacterial topoisomerase IV and DNA gyrase proteins required for DNA replication, translation, repair and recombination.
Administration & Dosage
0.5% eye drop: Adults and children 1 year of age and older:
- Days 1 and 2: Instill 1-2 drops in the affected eye(s) every 2 hours while awake, up to 8 times per day.
- Days 3 through 7: Instill 1-2 drops in the affected eye(s) every 4 hours while awake, up to 4 times per day.
1.5% eye drop: Adults and children 6 years of age and older:
- Days 1 through 3: Instill one to two drops in the affected eye(s) every 30 minutes to 2 hours while awake and approximately 4 and 6 hours after retiring.
- Day 4 through treatment completion: Instill one to two drops in the affected eye(s) every 1 to 4 hours while awake.
Children <1 year: Safety and effectiveness of Levofloxacin below 1 year of age have not been established.
Interaction
Particular medicate interaction considers have not been conducted with levofloxacin eye drops. But the systemic organization of a few quinolones has been appeared to promote plasma concentrations of theophylline, meddled with the digestion system of caffeine and improve the impacts of the verbal anticoagulant warfarin and its subsidiaries.
Contraindications
It is contraindicated in patients with a history of touchiness to Levofloxacin, to other quinolones or to any of the components of this pharmaceutical.
Side Effect
Side impacts happened as it were roughly 1-3% of patients that will incorporate temporal obscured vision, fever, remote body sensation, migraine, transitory visual burning, visual torment or distress, pharyngitis and photophobia. In less than 1% of patients included unfavorably susceptible responses, top edema, visual dryness and visual tingling.
Pregnancy & Lactation
Side impacts happened as it were roughly 1-3% of patients which will incorporate transitory obscured vision, fever, outside body sensation, migraine, temporal visual burning, visual torment or inconvenience, pharyngitis, and photophobia. In less than 1% of patients included unfavorably susceptible responses, cover edema, visual dryness and visual tingling.
Precautions & Warnings
Delayed utilize may result within the excess of non-susceptible living beings, counting organisms. In case superinfection happens, cease utilize and organized elective treatment.
Therapeutic Class
4-Quinolone preparations
Storage Conditions
Protect from light and moisture by storing below 30°C. Keep the medicine out of children’s reach.