Indications of Eclo 10 Cream

Moderate to severe corticosteroid-responsive dermatoses. Treatment of more resistant dermatoses eg. Stubborn eczemas, psoriasis, recalcitrant eczemas, lichen planus, discoid lupus, erythematosus, and other conditions which do not respond satisfactorily to less active steroids.

Pharmacology of Eclo 10 Cream

Clobetasol Propionate is a topical corticosteroid with a high potency. It works as an anti-inflammatory, anti-pruritic, and vasoconstrictor. It inhibits late-phase allergic reactions by exhibiting anti-inflammatory effects through different pathways. Mast cell density, chemotaxis, and eosinophil activation are all reduced. It also inhibits the metabolism of arachidonic acid and decreases cytokine production.

Dosage & Administration of Eclo 10 Cream

Apply sparingly 1-2 times daily for up to 4 weeks, reducing frequency as the condition responds.

Interactions of Eclo 10 Cream

Corticosteroid metabolism has been demonstrated to be inhibited by co-administered medications that inhibit CYP3A4 (e.g., ritonavir, itraconazole), resulting in increased systemic exposure.

Contraindications

Untreated bacterial, fungal, or viral skin lesions.

Side-Effects of Eclo 10 Cream

Side effects from clobetasol use are rare; but local side effects from the use of clobetasol include: Atrophic changes, such as striae, thinning of the skin; dilatation of the superficial blood vessels; spread and worsening of untreated infection; acne at the site of application in some patients

Pregnancy & Lactation

Eclo is safe to use in pregnancy and lactation.

Precautions & Warnings

Children, especially babies, are particularly susceptible to the side effects of clobetasol. So avoid prolong clobetasol use in infants and children and on the face.

Therapeutic Class

Other Topical corticosteroids

Storage Conditions

Store at below 30°C temperature, protected from light and moisture. Do not freeze. Keep out of the reach of children.

Pharmaceutical Name of Eclo 10 Cream

General Pharmaceuticals Ltd

Generic of Eclo 10 Cream

Clobetasol Propionate