Dulox 20 MG


Dulox 20 MG


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Indications of Dulox 20

Major Depressive Disorder (MDD)

Generalized Anxiety Disorder (GAD)

Diabetic Peripheral Neuropathic Pain (DPNP)


Pharmaceutical Name of Dulox 20

ACME Laboratories Ltd.



Duloxetine Hydrochloride is a selective serotonin and norepinephrine reuptake inhibitor (SSNRI) for oral administration.


Dosage & Administration

Some patients may benefit from starting at 30 mg once daily. There is no evidence that doses greater than 60 mg/day confers an additional benefit, while some adverse reactions were observed to be dose-dependent. A gradual dose reduction is recommended to avoid discontinuation symptoms.


Interaction of Dulox 20

Both CYP1A2 and CYP2D6 isozymes are responsible for Duloxetine metabolism. When Duloxetine was co-administered with fluvoxamine, a potent CYP1A2 inhibitor, the AUC, Cmax, and t of Duloxetine was increased.



Duloxetine is contraindicated in patients with a known hypersensitivity to this drug or any of the inactive ingredients. Duloxetine is not approved for use in treating bipolar depression.


Side-Effects of Dulox 20

The most commonly observed adverse events in Duloxetine hydrochloride treated patients were nausea, dizziness, dry mouth, constipation, decreased appetite, fatigue, somnolence, increased sweating, hyperhidrosis, and asthenia.


Pregnancy & Lactation

regnancy Category C. There are no adequate and well-controlled studies in pregnant women; therefore, Duloxetine should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.


Precautions & Warnings

All patients being treated with antidepressants for any indication should be monitored appropriately and observed closely for clinical worsening, suicidality, and unusual changes in behavior, especially during the initial few months of a course of drug therapy, or at times of dose changes.


Therapeutic Class

Serotonin-norepinephrine reuptake inhibitor (SNRI)


Storage Conditions

Do not store above 30°C.


Generic of Dulox 20

Duloxetine Hydrochloride