Dophylin 200 MG


Dophylin 200 MG


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Indications of Dophylin 400

Doxophylline is used to treat asthma, COPD and bronchospasm.


Pharmaceutical Name

ACME Laboratories Ltd.


Doxophylline may be a novel bronchodilator. It basically varies from Theophylline due to the nearness of a dioxolane gather in position 7. Doxophylline specifically hinders phosphodiesterase 4 in this manner unwinds bronchial smooth muscle. Be that as it mayin an unexpected way from Theophylline, Doxophylline shows up to have diminished affinities toward adenosine A1 and A2 receptors, which may account for the way better security profile of the sedate. Doxophylline is detailed to restrain platelet actuating figure (PAF) and era of leukotriene generation.


Administration & Dosage

Elderly: 200 mg tablet two or three times daily.

Adults: 400 mg tablet two or three times daily or as prescribed by the physician.


  • >12 years of age: 10 ml syrup or 200 mg tablet two or three times daily.
  • 6-12 years of age: 6-9 mg/kg body weight two times daily, i.e. if body weight is 10 kg, 3 ml (60 mg) two times daily or as prescribed by the physician.

If required daily dose of Doxophylline is 400 mg then Doxophylline SR tablet to be taken once daily or as prescribed by the physician


Interaction of Dophylin 400

Doxophylline ought to not be managed along side other xanthine subsidiariesHarmful synergism with ephedrine has been reported for xanthines. Like other xanthines, concomitant treatment with troleandomycin, lincomycin, clindamycin, allopurinol, cimetidine, ranitidine, propranolol and anti-flu immunization may diminish the hepatic clearance of xanthines causing an increment in blood levels. No prove of a relationship between Doxophylline serum concentrations and harmful occasions have been detailed.



Doxophylline is contraindicated in acute myocardial infarction. It is also contraindicated in patients with hypotension, in lactating women & patients who have shown hypersensitivity to its components.


Side Effects of Dophylin 400

Doxophylline rarely causes serious side effects, however possible side effects are similar for taking excess amount of caffeine. These include: nausea, vomiting, headache, upset stomach and heartburn.


Pregnancy & Lactation

Animal reproduction studies indicate that, Doxophylline does not cause fetal harm when administered to pregnant animals or can not affect reproduction capacity. However, since there is limited experience in human during pregnancy, xanthines should be given to pregnant women only if clearly needed. Doxophylline is contraindicated in nursing mothers.


Precautions & Warnings

The half-life of xanthine subsidiaries is impacted by a number of known factors. It may be delayed in patients with liver malady, in patients with congestive heart disappointment and in those patients taking certain other drugs like erythromycin, troleandomycin, lincomycin, allopurinol, cimetidine, propanolol and anti-flu antibody. In these cases, a lower measurements of Doxophylline may be required. Phenytoin, other anticonvulsants and smoking may cause an increment in clearance with a shorter cruel half-life. In these cases higher measurements of Doxophylline may be req


Therapeutic Class

Bronchodilator, Methyl xanthine derivatives


Storage Conditions

Protect from light and moisture by storing below 30°C. Keep the medicine out of children’s reach.


Generic of Dophylin 400