Dextrobac 5 ML


Dextrobac 5 ML


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Indications of Dextrobac

This sterile Eye Suspension is used to treat steroid-responsive inflammatory ocular diseases in which a corticosteroid is prescribed yet there is a risk of bacterial eye infection.

Pharmaceutical Name of Dextrobac

Incepta Pharmaceuticals Ltd.


Tobramycin’s bactericidal activity is achieved, like that of other amino-glycosides, by inhibiting normal protein synthesis in susceptible bacteria, but nothing is understood about how this action works at the moment. Protein synthesis suppression is hypothesized to be caused by a ribosome activity that causes bacterial messenger RNA misreading. Dexamethasone works by inhibiting phospholipase A2, which is the first step in prostaglandin formation. Dexamethasone also prevents neutrophils from chemo-tactically infiltrating the inflammatory site. As a result, its anti-inflammatory activity has increased by 25 times, and its overall therapeutic effectiveness has increased by 8-10 times.

Dosage & Administration

Insert 1 drop into the conjunctival sac 3-5 times per day. During the initial 24 to 48 hours, the dosage may be increased to 1 drop every 2 hours.

Interaction of Dextrobac

This combination eye drop has not been subjected to any particular interaction studies. In the case of simultaneous therapy with other topical ophthalmic drugs, a 10-minute delay between applications should be given.


Vaccinia, varicella, and other viral diseases of the cornea and conjunctiva. Epithelial herpes simplex keratitis (dendritic keratitis), vaccinia, varicella, and other viral diseases of the cornea and conjunctiva. Acid-fast bacilli such as Mycobacterium TB, Mycobacterium leprae, and Mycobacterium avium can cause mycobacterial infections of the eye. Infections of the ocular structures caused by fungi. A purulent infection of the eye that has gone untreated. Any component of the drug causes hypersensitivity.

Side Effects of Dextrobac

Localized ocular toxicity and hypersensitivity, including lid irritation and swelling, as well as conjunctival erythema, are the most common side effects of topical ocular Tobramycin. The steroid component causes an increase in intraocular pressure (IOP), which can lead to glaucoma and infrequent optic nerve injury, as well as the production of posterior subcapsular cataracts.

Pregnancy & Lactation

It has not been determined whether or not it is safe to use during pregnancy and lactation in humans.

Precautions & Warnings

Before using, give the bottle a good shake. To avoid contamination, avoid touching the bottle’s tip to the affected eye, eyelid, or any other surface of the affected eye. After each usage, carefully shut the bottle.

Therapeutic Class

Ophthalmic steroid – antibiotic combined preparations

Storage Conditions

Keep the temperature below 30°C and away from light and moisture. Keep out of children’s reach.

Generic of Dextrobac

Dexamethasone + Tobramycin