Indications of Dexagen T 5 ml

For the treatment of inflammatory ocular diseases that respond to corticosteroids and in which bacterial infection or the risk of bacterial eye infection occurs. This is not intended for use in children.

Pharmaceutical Name of Dexagen T 5 ml

General Pharmaceuticals Ltd.

Pharmacology

Like other amino-glycosides, the bactericidal action of Tobramycin is fulfilled by particular hindrance of typical protein union in vulnerable microscopic organisms, but at the display time, exceptionally small is known approximately this activity. It is thought that restraint of protein union is due to an activity on ribosome that causes bacterial misreading of flag-bearer RNA. The activity of Dexamethasone is to restrain the phospholipase A2, the primary step in prostaglandin union. Moreover Dexamethasone hinders the chemo-tactic invasion of neutrophils into the location of irritation. The result is that its anti-inflammatory movement is 25 times more prominent and its in general restorative adequacy 8-10 times more prominent than that of hydrocortisone.

Dosage & Administration

Insert 1 drop into the conjunctival sac 3-5 times per day. During the initial 24 to 48 hours, the dosage may be increased to 1 drop every 2 hours.

Interaction of Dexagen T 5 ml

With this combination of eye drops, no particular interaction studies have been conducted. There should be a 10-minute delay between administrations if other topical ophthalmic drugs are being used concurrently.

Contraindications

As well as vaccinated and varicellated cornea and conjunctiva, there are many additional viral diseases that can affect the cornea and conjunctiva. For example, acid-fast bacilli like Mycobacterium TB, Leprae, or Avium can cause eye infections caused by a germ called Mycobacterium tuberculosis. Fungal infections of the eye. Infections of the eyes that are not treated. Hypersensitivity to any of the medication’s components

Side Effects of Dexagen T 5 ml

Most common side effects of topical ocular Tobramycin are ocular hypersensitivity and localized ocular toxicity. IOP increase with the development of glaucoma, optic nerve injury, posterior subcapsule cataract formation are side effects of the steroid component.

Pregnancy & Lactation

In humans, it has not been shown safe to use during pregnancy and breastfeeding

Precautions & Warnings

Pour the contents into a clean, dry bottle. In order to avoid contamination, do not put your fingertip or any other part of the container near the affected eye or eyelid. Close the bottle carefully after use.

Therapeutic Class

Ophthalmic steroid – antibiotic combined preparations

Storage Conditions

Generic of Dexagen T 5 ml

Dexamethasone + Tobramycin